RNA Analytical Quality/Resources

1. Pre-Banking And Avoiding Manufacturing Challenges For GMP Plasmids Containing Unstable Sequence Regions 4/21/2021

   Ensuring consistent replication and proper retention of plasmid DNA sequence is vital to the economics and efficiency in generating starting materials used for production of AAV delivered gene therapy and mRNA vaccines and therapeutics.

2. CRISPR sgRNA For Successful Gene Editing: Discovery To Clinic 9/25/2023

   The single guide RNA (sgRNA) is one of the key components of successful CRISPR gene editing. Here we cover all the important aspects of sgRNA and Synthego’s sgRNA products.

3. Quality Assurance In IVT RNA Vaccine Development Using Electrophoresis 2/20/2025

   Discover advanced solutions for IVT RNA synthesis, focusing on enhancing fidelity in throughput, innovative technologies, and methodologies to optimize your RNA research and development processes.

4. Top 8 Benefits Of Mass Spectrometry Imaging Early In Drug Development 9/1/2024

   Here we explore the top 8 benefits of using mass spectrometry imaging in the oncology drug discovery and early development stages.

5. Twist Of Two: 2D-LC For Oligos 12/16/2025

   Discover how coupling orthogonal mechanisms reveals hidden impurities and creates a more robust strategy for characterizing complex oligonucleotide samples.

6. CRISPR Off-Target Editing: Prediction, Analysis, And More 2/28/2025

   A crucial consideration for researchers is off-target editing – unintended DNA modifications at sites other than the intended target. Explore the complexities and strategies to mitigate these effects.

7. Oligonucleotides: Where We Are And Where We Would Like To Go  9/8/2024

   This presentation provides an overview of oligonucleotide bioanalysis's current status and future directions. We will look into the advantages and disadvantages of various bioanalytical techniques.

8. Quantification Of Large Oligonucleotides Using High Resolution MS/MS 3/4/2022

   Explore how to achieve sensitive, high-resolution analysis of large oligonucleotides, with the opportunity to perform both qualitative and quantitative analysis in a single run.

9. Top 5 Approaches To The Bioanalysis Of Oligonucleotides 9/1/2024

   Evaluate the strengths and limitations of each bioanalysis method carefully to choose the most effective strategy for your clinical study.

10. Automated NGS Solutions Advance Rare Disease Research 2/27/2026

    See how a unified NGS workflow is helping a major pediatric genetics lab boost efficiency, manage growing sample volumes, and accelerate insights into rare diseases through streamlined automation.