Welcome to Advancing RNA Live – An interactive forum to discuss the most important technologies and trends impacting the rapidly evolving field of RNA-based therapeutics.Throughout the year our editors sit down with industry experts to discuss how biopharmaceutical companies address various challenges in RNA therapy development, including analytical, quality, manufacturing, and regulatory issues. These discussions often include Q&A sessions with attendees, and each Advancing RNA Live session will be archived and accessible at any time by registered site users.
ACHIEVING NEXT-GENERATION MRNA-LNP THERAPEUTICS DELIVERY
Achieving Next-Generation mRNA-LNP Therapeutics Delivery
It’s impossible to attend an event on the future of RNA therapeutics without hearing about the challenges we’re facing with targeted RNA-LNP delivery. In this final Advancing RNA Live discussion of 2024, we sat down with three LNP experts to parse out...
FROM BOTTLENECK TO BREAKTHROUGH: REIMAGINING THE MRNA THERAPEUTICS SUPPLY CHAIN
From Bottleneck To Breakthrough: Reimagining The mRNA Therapeutics Supply Chain
The supply chain for mRNA-based cell and gene therapies presents unique challenges due to the sensitive nature of these products. And, as mRNA technology continues to advance, robust processes and scalable solutions are necessary to meet increasing demand.
CAN WE DO BETTER? CURRENT & FUTURE REALITIES OF MRNA PROCESS DEVELOPMENT
Can We Do Better? Current & Future Realities of mRNA Process Development
There’s been great progress in establishing processes and platforms for linear mRNA vaccines — but where does this current know-how fall short for those exploring linear and next-gen RNA constructs for therapeutic (non-vaccine) products?
MEET OUR HOST
Anna Rose Welch is the editorial and community director of Advancing RNA. Over the past decade, her work in the biologics and advanced therapies spaces has taken her across the world to chair conferences, give presentations, moderate panel discussions, and serve on conference advisory boards. In 2018, her first book of poetry, We, The Almighty Fires, was published by Alice James Books.
OPENING THE “BLACK BOX” OF THE MRNA REGULATORY PARADIGM
Opening The "Black Box" Of The mRNA Regulatory Paradigm
This Advancing RNA panel discussion covers the broad learnings therapeutics developers can (or can’t) adapt from the previously approved mRNA vaccine products, and what an “ideal” RNA therapeutics regulatory paradigm could look like
GOT RAW MATERIALS? THE STATE OF THE MRNA SUPPLY CHAIN
Got Raw Materials? The State Of The mRNA Supply Chain
This discussion delves into how Advancing RNA can address concerns over the current “health” and availability of both small- and large-scale RNA therapeutics.
REVOLUTIONARY INCREMENTALISM FUTURE-PROOFING MRNA DRUG MANUFACTURING
Revolutionary Incrementalism: Future-Proofing mRNA Drug Manufacturing
Industry experts share go-to best practices, suggestions, and experiences for prioritizing and streamlining technical operations endeavors to prepare mRNA therapeutics companies for the clinic and, eventually, the commercial market.
RISK REDUCTION IN MRNA THERAPEUTIC DEVELOPMENT
Risk Reduction In mRNA Therapeutic Development
mRNA is at an inflection point. To reach its therapeutic potential in chronic, and even rare, disease applications, some biopharmaceutical manufacturing fundamentals must be addressed.
MRNA UPDATE: BEYOND PROPHYLACTIC VACCINES
mRNA Update: Beyond Prophylactic Vaccines
mRNA-based therapeutics are widely regarded as a “next big thing” in biopharma, but manufacturing them is fraught with complex challenges. Check out this digital event from Bioprocess Online Live featuring a discussion with mRNA process development experts on ...
MAJOR TRENDS IN NEXT-GEN RNA ENGINEERING
Major Trends In Next-Gen RNA Engineering
From tissue specificity to potency and durability, major trends in RNA are developing as the space continues to evolve at record-breaking speed. In June 2023, Cell & Gene Live welcomed Nathaniel Wang, CEO and Co-Founder, Replicate Bioscience and Sam Deutch, E...
ADVANCEMENTS IN TARGETED MRNA DELIVERY
Advancements In Targeted mRNA Delivery
mRNA has broad potential as a therapeutic. The clinical translation of mRNA therapeutics has been made possible through advances in the design of mRNA manufacturing and intracellular delivery methods. However, broad application of mRNA is still limited by the need for imp...
LNPS & BEYOND: OPPORTUNITIES IN RNA DELIVERY
LNPs & Beyond: Opportunities In RNA Delivery
The rapid development, scale-up, and successful commercialization of mRNA vaccines served as a great case study on the importance of mRNA/RNA therapeutics. For those striving to develop next-gen RNA therapeutics, achieving more specifically targeted non-viral deliver...
