Calviri has been developing an RNA vaccine to prevent cancer for more than 20 years and repeatedly faced the nearly universal belief that it’s impossible. We’ve learned a number of important lessons along the way that are worth imparting to other vaccine developers.
- 6 PEG Alternatives You Should Be Thinking About
- Achieving Flexibility In RNA Drug Manufacturing With Microfluidics
- Modular And Single-use Tech Driving The Future Of Biomanufacturing
- What We Need To Unlock Next-Generation mRNA Therapeutics
- What Regenerative Medicine Manufacturers Have Been Waiting For
- New Developments In mRNA Vaccine Efficacy Show Promise
- FDA Sets Recommendations For Predicting Dangerous Nitrosamine Impurities
- Oh, Oligonucleotides! Everybody Wants In
ON DEMAND WEBINARS
Large scale production of plasmid DNA requires an in-depth understanding and optimization of the entire downstream process. Explore a complete solution, from harvest to bulk filtration.
How PCR-based technology can accelerate mRNA development and manufacturing and design principles/critical parameters to enable the rapid development of lipids for RNA formulation.
Explore why process-related impurities are a concern in vaccines and present results and learnings from LC-MS analyses of several mRNA- and protein-based vaccines for COVID-19.
Discover how to integrate appropriate materials and tools for oligonucleotide handling, optimize DNA storage using dedicated fluoropolymer film, perform complex biochemical reactions in bags, and more.
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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![GettyImages-1387090964 cell and gene therapy]( "Moving CGTx Clinical Development Forward In 2023")
Moving CGTx Clinical Development Forward In 2023Gain insights on cell and gene therapy (CGTx) clinical trial design and commercialization strategies as a panel of industry experts share their considerations.
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![GettyImages-1357908552]( "Leveraging Single-Use Technology For mRNA-LNP Drug Manufacturing")
Leveraging Single-Use Technology For mRNA-LNP Drug ManufacturingSingle-use technology is vital for ensuring the quality and expedited market entry of genomic medicines. Learn how LNP technology is paving the way for a new era of personalized, precise medicine.
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![Solving Challenges Puzzle Maze]( "RNA: The Next Era In Therapeutic Development")
RNA: The Next Era In Therapeutic DevelopmentReview the unique set of challenges for RNA production that must be considered and solved to reach their full therapeutic potential.
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![GettyImages-1445640967 RNA therapy]( "RNA Therapies – Global Clinical Trial Landscape - Focus On Asia Pacific")
RNA Therapies – Global Clinical Trial Landscape - Focus On Asia PacificLearn about the global clinical trial landscape of RNA therapy, with emphasis on trends in the Asia Pacific, and recent advancements in the field.
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![Lipid Nanoparticle mRNA Vaccine GettyImages-1418152448]( "Fit-For-Purpose Lipids Can Accelerate, Scale, And Improve RNA-LNP Drugs")
Fit-For-Purpose Lipids Can Accelerate, Scale, And Improve RNA-LNP DrugsEmerging biotech companies are investing in novel delivery capabilities to address different modalities' needs and extra-hepatic delivery. Explore steps to accelerate commercial nanomedicine delivery.
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![Gene Therapy GettyImages-1164556175]( "mRNA Product IVT Process Insights")
mRNA Product IVT Process InsightsIn vitro transcription (IVT) allows a researcher to tailor synthesis and introduce modifications to produce a transcript. Learn about IVT along with process challenges and strategies.
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![GettyImages-1404945060 Medical Lab]( "mRNA: How To Build A Custom Program Using CDMO Services")
mRNA: How To Build A Custom Program Using CDMO ServicesDevelopment of RNA-based therapies sits at the cutting edge of vaccine and oncology innovation, in addition to holding promise in dozens of other therapeutic areas.
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![GettyImages-919410014-dna-gene-therapy-future-technology]( "Purification Of DNA Oligonucleotides Using An Anion Exchange Resin")
Purification Of DNA Oligonucleotides Using An Anion Exchange ResinLearn how a strong anion exchange resin can be used for the efficient purification of single-stranded DNA oligonucleotides used in clinical trials.
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![Molecule]( "mRNA-LNP Nucleic Acid Assessment From Distinct Formulations")
mRNA-LNP Nucleic Acid Assessment From Distinct FormulationsReview a showcase of a high throughput robust analysis for nucleic acid integrity and size assessment of mRNA-LNP samples using a multi-capillary system and purity and integrity analysis kit.
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![Scientist Laboratory sample pipette GettyImages-1354172647]( "Determining RNA Integrity And Purity By Capillary Gel Electrophoresis")
Determining RNA Integrity And Purity By Capillary Gel ElectrophoresisTo ensure mRNA product quality, it's important to confirm the integrity of the RNA. Examine the results of a study challenging the performance of the CGE method in assessing mRNA integrity and purity.
