ARW ON RNA
Stay "Stereocurious": What The Future Holds For Oligo Quality
Overall, there were two areas of discussion at TIDES that demonstrate the amount of growth we have yet to do as a space — particularly in the realms of regulatory development and quality. As I intend to showcase here in part 1 of this muti-part article, this year’s TIDES was a great reflection of the tension(s) that can arise as we realize how much space exists between where we are and where we’re going next.
OUR EXPERT NETWORK
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The Missing Partners In microRNA Silencing: What QKI Reveals About RNA Regulatory Complexity
New research suggests microRNA silencing depends on RNA-binding protein partners like QKI, revealing a more complex regulatory network shaping gene expression.
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The Hidden Bottleneck In Advanced Therapies Isn't Science… It's Translational Friction
Scientific breakthroughs may spark innovation, but operational excellence ultimately determines which advanced therapies reach patients.
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RNA Therapeutics: Why CMC Strategy Will Define The Next Decade
As RNA matures into an industrial platform, long-term success will depend less on discovery and more on scalable CMC systems, integration, and execution.
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Rethinking The Oligonucleotide Backbone: Why RNA Therapeutics May Need A New Molecular Design Framework
New backbone chemistries could unlock greater control over delivery, specificity, and safety, expanding the molecular design space for RNA medicines.
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RNA Platforms: What Transfers And What Breaks
A practical framework for distinguishing reusable RNA platform knowledge from biology-specific unknowns as therapeutics expand into new tissues and indications.
WEBINARS
MEET ARW

I’ve spent the past 10 years building relationships across the biologics and advanced therapies industry. In addition to hosting conversations and writing thought leadership articles, my goal as the editorial and community director for Advancing RNA is to find creative ways for the RNA (and broader ATMP) space to discuss, debate, and ultimately define a mature RNA therapeutics industry.
Start the conversation by following me on LinkedIn!
RNA HOT TAKES
- Which mRNA-LNP Attributes Deserve Deeper Characterization Today?
- Sticks, Carrots, & Carolina Reapers: Fact-Checking The "Death" Of The US mRNA Industry
- mRNA Hot Takes: Ghost Peppers & Global R&D
- mRNA Hot Takes: Habaneros & Headwinds
- The Trough Of Disillusionment: 2026 RNA Reality Checks
- mRNA Hot Takes: Fighting Complacency And "Alternative Facts" In 2026
- mRNA Hot Takes: Building A Solid Foundation For Your RNA Company & Products
VIRTUAL EVENTS
- Evolutions in mRNA Drug Product Analytical Development
- Closing The Adoption Gap For Advanced Single-Use Materials
- Advancements in gRNA Manufacturing & Quality
- Chemoenzymatic Ligation: A New Frontier In siRNA Manufacturing
- Advancements In Targeted LNP Therapy
- Unlocking The Future: Innovations In The mRNA And Oligo Supply Chains
NEWSLETTER ARCHIVE
- 06.24.26 -- What Makes An RNA Platform Investable?
- 06.17.26 -- Why Chemoenzymatic Ligation Is Non-Negotiable In siRNA Manufacturing
- 06.10.26 -- Order, Chaos, & The mRNA Black Box: Takeaways From The USP/AMM Forum
- 06.06.26 -- Advancing RNA Newsletter Best Of May
- 06.03.26 -- What's Holding Us Back From Enzymatic siRNA Production?
- 05.27.26 -- Modernizing Oligonucleotide Synthesis