ARW ON RNA
Targeting The Uncharted Heart: Why The Next Era Of siRNA Belongs In Cardiology
During our conversation, Gallagher walked me through what’s keeping her up at night as she leads the company and its first siRNA candidate toward an IND, elaborating on the role RNA can play in cardiomyopathies and identifying the unique challenges of developing RNA medicines today.
OUR EXPERT NETWORK
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Structure-Guided siRNA Design: How Chemistry, Context, And Constraint Are Shaping The Next Phase Of RNAi Therapeutics
As siRNA design matures, the next breakthroughs will depend on balancing chemical optimization, delivery challenges, and expanding beyond established design rules.
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Scaling RNA Therapeutics: Purification, LNP Formulation, And GMP Manufacturing (Pt. 2)
Part 2 explores the downstream technologies that turn RNA into a therapeutic product, from impurity removal and LNP formulation to GMP infrastructure and scalable manufacturing.
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From Exosomes To Nanodrugs: Advancing Therapeutic Delivery For CNS Repair
Exosomes are biological vesicles used for cellular communication that can overcome CNS barriers, delivering therapeutic cargo for CNS and optic nerve injuries.
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Why RNAi-Based Oncology Must Move Beyond Single-Target Thinking
RNAi therapeutics may help oncology move beyond single-target drugs by disrupting adaptive tumor survival networks driving resistance in solid tumors.
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What Makes An RNA Platform Investable? Lessons From The Last Wave Of Biotech Financing
RNA investing has shifted from hype to scalability, forcing companies to prove manufacturability, delivery strength, and platform-wide value.
WEBINARS
MEET ARW

I’ve spent the past 10 years building relationships across the biologics and advanced therapies industry. In addition to hosting conversations and writing thought leadership articles, my goal as the editorial and community director for Advancing RNA is to find creative ways for the RNA (and broader ATMP) space to discuss, debate, and ultimately define a mature RNA therapeutics industry.
Start the conversation by following me on LinkedIn!
RNA HOT TAKES
- Which mRNA-LNP Attributes Deserve Deeper Characterization Today?
- Sticks, Carrots, & Carolina Reapers: Fact-Checking The "Death" Of The US mRNA Industry
- mRNA Hot Takes: Ghost Peppers & Global R&D
- mRNA Hot Takes: Habaneros & Headwinds
- The Trough Of Disillusionment: 2026 RNA Reality Checks
- mRNA Hot Takes: Fighting Complacency And "Alternative Facts" In 2026
- mRNA Hot Takes: Building A Solid Foundation For Your RNA Company & Products
VIRTUAL EVENTS
- Evolutions in mRNA Drug Product Analytical Development
- Closing The Adoption Gap For Advanced Single-Use Materials
- Advancements in gRNA Manufacturing & Quality
- Chemoenzymatic Ligation: A New Frontier In siRNA Manufacturing
- Advancements In Targeted LNP Therapy
- Unlocking The Future: Innovations In The mRNA And Oligo Supply Chains
NEWSLETTER ARCHIVE
- 06.10.26 -- Order, Chaos, & The mRNA Black Box: Takeaways From The USP/AMM Forum
- 06.06.26 -- Advancing RNA Newsletter Best Of May
- 06.03.26 -- What's Holding Us Back From Enzymatic siRNA Production?
- 05.27.26 -- Modernizing Oligonucleotide Synthesis
- 05.22.26 -- Scaling RNA & LNP Manufacturing With Smarter Analytics
- 05.13.26 -- Simplify The Journey Of Advancing Your Therapies To Patients