RNA Analytical Quality/Resources

  1. Elevating mRNA Manufacturing Toward GMP-Readiness 8/27/2025

    The mRNA Technology Transfer Program empowers LMICs with scalable vaccine production. Learn about a partnership that drives innovation in mRNA and sets a global blueprint for equitable health access.

  2. High-Throughput Characterization Of RNA 5/9/2022

    How a multi-capillary electrophoresis (CE) system is used to efficiently separate a wide range of RNA-based molecules by size and demonstrates the multiplex capability for RNA characterization.

  3. Quantification Of Large Oligonucleotides Using High Resolution MS/MS 3/4/2022

    Explore how to achieve sensitive, high-resolution analysis of large oligonucleotides, with the opportunity to perform both qualitative and quantitative analysis in a single run.

  4. Determining RNA Integrity And Purity By Capillary Gel Electrophoresis 6/30/2023

    To ensure mRNA product quality, it's important to confirm the integrity of the RNA. Examine the results of a study challenging the performance of the CGE method in assessing mRNA integrity and purity.

  5. Future-Proofing mRNA Drug Manufacturing: The Value of Continuous Improvement 4/30/2024

    With so many uncertainties permeating the mRNA market, this largely preclinical industry is still seeking answers on how to reach successful therapeutic development. Identifying optimizations, both sequence-dependent and otherwise, to enhance the manufacturing process is crucial for advancing mRNA product development, which holds vast potential to address a wide range of indications.

  6. Expression Analysis Of CTLA-4, PD-1, And PD-L1 4/23/2025

    Advance personalized immunotherapy in NSCLC by leveraging qPCR-based analysis of CTLA-4, PD-1, and PD-L1 expression to identify predictive biomarkers and guide more effective treatment strategies.

  7. Learn How Compliance-Ready LC-MS Workflows for Oligonucleotides Can Expand your Analytical Services Portfolio 2/22/2022

    CMO invests in solution to ensure data integrity and meet regulatory requirements as they expand their oligonucleotide manufacturing and analysis services.

  8. Structural Characterization Of RNA And Detection Of RNA-Ligand Binding 1/13/2025

    Delve into the intricacies of riboswitch behavior and ligand interactions and gain valuable insights into gene regulation and potential therapeutic targets.

  9. Boost LNP Drug Potency With Optimized Delivery Formulations 11/21/2022

    Lipid nanoparticles (LNPs) function as a drug delivery system for nucleic acids. Learn about the biomedical applications of LNPs as well as the anatomy, formulation optimization, and safety of LNPs.

  10. Top 5 Approaches To The Bioanalysis Of Oligonucleotides 9/1/2024

    Evaluate the strengths and limitations of each bioanalysis method carefully to choose the most effective strategy for your clinical study.