RNA Analytical Quality/Resources

  1. A&M STABTEST Expands Service Offerings In Protein And Oligonucleotide Analysis With LC-MS System 2/22/2022

    CRO upgrades systems to provide regulatory compliance for large-molecule protein analysis, expanding their oligonucleotides capabilities.

  2. Unlocking The IP Benefits Of Novel Nucleases In CRISPR Therapies 10/28/2024

    Incorporating novel nucleases into CRISPR therapies enhances intellectual property benefits through improved licensing, strategic protections, and access to new gene targets.

  3. Precision In Nanoparticle Processing And Monodispersed Lipid Nanoparticles For Advanced Therapeutics 11/17/2025

    Precision in nanoparticle processing is key for drug delivery and vaccines. Learn how monodispersed formulations enhance reproducibility and stability for next-generation therapeutics, like RNA-LNPs.

  4. Why Bioanalysis Needs To Break Free From Manual Bottlenecks 9/2/2025

    Bioanalysis remains one of the most persistent bottlenecks in drug development, with CROs displaying inefficiencies that are no longer operational nuisances but strategic liabilities.

  5. Leveraging Filtration Plates To Accelerate The Detection Of Vitamin B6 In Clinical Samples For Research Purposes 6/9/2022

    By employing a simple strategy many different lab protocols where filtration is required can be accelerated. Learn more about automation-friendly 96-well filter plates that enable more samples to be filtered in one go.

  6. Exploring Osmolality As A CQA Within RNA Therapeutics 10/3/2023

    Discover how osmolality can be applied throughout the bioprocessing workflow for RNA, and recognize the importance of this sensitive measurement, from formulation optimization to cryopreservation techniques.

  7. Exploring The Spatial Distribution Of mRNA-Lipid Nanoparticles Using MALDI MSI 4/23/2025

    Learn how leveraging high-resolution MALDI-MSI can advance the development of lipid nanoparticle-based therapies, uncovering spatial biodistribution, pharmacokinetics, and organ-specific variability.

  8. Quantification Of Large Oligonucleotides Using High Resolution MS/MS 3/4/2022

    Explore how to achieve sensitive, high-resolution analysis of large oligonucleotides, with the opportunity to perform both qualitative and quantitative analysis in a single run.

  9. Ultra-Sensitive Assay For Anti-Sense Oligonucleotide Quantification 3/1/2022

    Learn about a new level in sensitivity for challenging analytes in matrix that opens doors for accurate bioanalysis and metabolism studies with specificity not achievable with orthogonal methods.

  10. Assigning IR Absorption Bands For RNA Building Blocks Using Microfluidic Modulation Spectroscopy 1/13/2025

    Explore the power of MMS in identifying RNA base signatures. This study analyzes vibrational modes of A, G, C, and U, revealing insights into electronic environments and molecular interactions.