RNA Analytical Quality/Resources

  1. RNA: The Next Era In Therapeutic Development 7/26/2023

    Review the unique set of challenges for RNA production that must be considered and solved to reach their full therapeutic potential.

  2. Elevating mRNA Manufacturing Toward GMP-Readiness 8/27/2025

    The mRNA Technology Transfer Program empowers LMICs with scalable vaccine production. Learn about a partnership that drives innovation in mRNA and sets a global blueprint for equitable health access.

  3. Stick With Me: The Cool Chemistry Of HILIC Oligonucleotide Analysis 12/15/2025

    Discover a powerful alternative for analyzing polar sequences without ion-pairing reagents. By leveraging hydrophilic partitioning, you can achieve sharper separation and improved mass spectrometry compatibility.

  4. Assessing Doggybone DNA For In Vitro Transcription 4/26/2024

    In this study, we evaluated the performance of two dbDNA IVT templates, each encoding the same mRNA (firefly luciferase or Fluc), by looking at the mRNA purity and in vivo potency of the mRNA IVT’d from each template.

  5. Demystifying CRISPR gRNA Chemical Modifications 10/28/2024

    Chemical modifications on CRISPR gRNAs enhance stability, editing efficiency, and reduce immune responses, enabling in vivo applications and clinical success.

  6. Why Bioanalysis Needs To Break Free From Manual Bottlenecks 9/2/2025

    Bioanalysis remains one of the most persistent bottlenecks in drug development, with CROs displaying inefficiencies that are no longer operational nuisances but strategic liabilities.

  7. Establishing Analytical Methods For mRNA-Based Therapies 6/13/2023

    Here, we provide a detailed description of assays for sequence identification and LNP composition in mRNA-LNP products that support the development of safe and effective mRNA therapies.

  8. Oligonucleotides: Where We Are And Where We Would Like To Go  9/8/2024

    This presentation provides an overview of oligonucleotide bioanalysis's current status and future directions. We will look into the advantages and disadvantages of various bioanalytical techniques.

  9. Biopharma Production And Quality Control With Electrophoresis 2/20/2025

    Discover how Kaneka Eurogentec, a leading provider of custom DNA synthesis and molecular biology services, enhanced their fragment analysis to achieve higher efficiency and accuracy in their workflows.

  10. Reduce Contamination Risks When Storing Synthetic DNA 10/30/2023

    An alternative to traditional polyethylene bags is offering cell and gene therapy manufacturers a solution to contamination concerns regarding DNA or RNA fragments.