RNA Analytical Quality/Resources

  1. IR Spectral Signatures Of GC, AU, And GU Base Pairing In H2O-Based Buffer By MMS 5/22/2025

    Explore a label-free approach to characterize RNA structure with high sensitivity. See how specific base pair types are resolved, providing a clearer picture of RNA folding.

  2. How A Drug's Molecule Type Affects Several Bioanalysis Parameters 9/1/2024

    Discover why bioanalytics are crucial to selecting promising drug candidates during development and to characterizing the pharmacokinetic and pharmacodynamic profile of the drug in early clinical trials.

  3. Reduce Contamination Risks When Storing Synthetic DNA 10/30/2023

    An alternative to traditional polyethylene bags is offering cell and gene therapy manufacturers a solution to contamination concerns regarding DNA or RNA fragments.

  4. Development Of Alternative BCDP Reagents For The Synthesis Of 5' -Terminal Phosphate Oligonucleotides 11/25/2025

    New alternative phosphitylating reagents reduce the safety hazards associated with BCDP, enabling a safer and effective synthesis of key oligonucleotide sequences.

  5. Preventive Control Of Sequencing Through The Insert 3/4/2026

    Understanding library size distributions helps prevent sequencing through the insert, reducing adapter read‑through. Explore how smear analysis guides optimal read‑length selection to avoid noise.

  6. Best Practices For Analysis Of IVT mRNA 11/20/2025

    Discover how an automated capillary electrophoresis system provides robust and precise integrity, concentration, and size analysis for IVT mRNA.

  7. Exploring The Spatial Distribution Of mRNA-Lipid Nanoparticles Using MALDI MSI 4/23/2025

    Learn how leveraging high-resolution MALDI-MSI can advance the development of lipid nanoparticle-based therapies, uncovering spatial biodistribution, pharmacokinetics, and organ-specific variability.

  8. Lessons From Benchmarking Of dsRNA Across Polymerase Systems 5/1/2026

    Not all low-dsRNA claims hold up under direct comparison. A 15-enzyme IVT study identifies the few systems that actually deliver across yield, integrity, and dsRNA simultaneously.

  9. Suitability Testing For IVT mRNA Analysis 11/20/2025

    Automated capillary electrophoresis provides robust, precise analysis of IVT mRNA integrity, concentration, and size, demonstrating excellent method precision.

  10. Boost LNP Drug Potency With Optimized Delivery Formulations 11/21/2022

    Lipid nanoparticles (LNPs) function as a drug delivery system for nucleic acids. Learn about the biomedical applications of LNPs as well as the anatomy, formulation optimization, and safety of LNPs.