RNA Analytical Quality/Resources
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How A Drug's Molecule Type Affects Several Bioanalysis Parameters
9/1/2024
Discover why bioanalytics are crucial to selecting promising drug candidates during development and to characterizing the pharmacokinetic and pharmacodynamic profile of the drug in early clinical trials.
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Oligonucleotides: Where We Are And Where We Would Like To Go
9/8/2024
This presentation provides an overview of oligonucleotide bioanalysis's current status and future directions. We will look into the advantages and disadvantages of various bioanalytical techniques.
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Assigning IR Absorption Bands For RNA Building Blocks Using Microfluidic Modulation Spectroscopy
1/13/2025
Explore the power of MMS in identifying RNA base signatures. This study analyzes vibrational modes of A, G, C, and U, revealing insights into electronic environments and molecular interactions.
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Biopharma Production And Quality Control With Electrophoresis
2/20/2025
Discover how Kaneka Eurogentec, a leading provider of custom DNA synthesis and molecular biology services, enhanced their fragment analysis to achieve higher efficiency and accuracy in their workflows.
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From Data To Decisions: Accelerating Your mRNA Drug Development With Analytics
11/20/2024
To stay ahead in the competitive landscape of mRNA development, adopt a comprehensive QC strategy today and begin conducting meaningful tests to ensure the quality of your test articles.
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Alternatives To CRISPR-Cas9: Nucleases For Next-Gen Therapy
10/28/2024
Alternatives to CRISPR-Cas9 address limitations like delivery challenges and off-target effects. Emerging nucleases offer improved specificity, smaller sizes, and therapeutic applications.
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Effects Of mRNA Capping Technologies
4/26/2024
This study compares two important mRNA capping technologies by evaluating the mRNA integrity, percent Cap1 content, dsRNA content, in vivo expression, and innate immune activation in mice.
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Lentiviral Vector Characterization For Cell And Gene Therapy Manufacturing
6/20/2024
This study focuses on characterizing recombinant LVVs used in gene-modified cell therapies, utilizing two real-time PCR assays adapted to the QuantStudio™ Absolute Q™ Digital PCR System.
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IR Spectral Signatures Of GC, AU, And GU Base Pairing In H2O-Based Buffer By MMS
5/22/2025
Explore a label-free approach to characterize RNA structure with high sensitivity. See how specific base pair types are resolved, providing a clearer picture of RNA folding.
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Structural Characterization Of RNA And Detection Of RNA-Ligand Binding
1/13/2025
Delve into the intricacies of riboswitch behavior and ligand interactions and gain valuable insights into gene regulation and potential therapeutic targets.