FORMULATION ARTICLES
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![Human anatomy, medical, biology, science, healthcare-GettyImages-1458871453]( "The Future Of Kidney Disease Therapeutics: Bringing Nanomedicine To Nephrology")
The Future Of Kidney Disease Therapeutics: Bringing Nanomedicine To NephrologyNanomedicines are solving the drug delivery problem in kidney disease. The next step: bridging the translational gap to advance these technologies into the clinic.
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![Molecular biology, mRNA strands, genetics-GettyImages-2198118160]( "Engineering Translation: How tRNA Therapeutics Expand The RNA Toolkit")
Engineering Translation: How tRNA Therapeutics Expand The RNA ToolkitEngineered tRNAs target translation itself — correcting shared errors like premature stop codons at the ribosome — to restore functional protein and redefine precision medicine by mechanism, not diagnosis.
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![Chromosomes with Telomere floating, science, anti aging technology-GettyImages-1486563542]( "Microneedle Delivery Of Telomerase Protects Skin From Radiation-Induced DNA Damage")
Microneedle Delivery Of Telomerase Protects Skin From Radiation-Induced DNA DamagePre-treatment with telomerase mRNA shields human skin from radiation-induced DNA damage, reducing radiotherapy side effects.
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![AI medical technology-GettyImages-2233342016]( "Targeted Delivery – A Holy Grail For CRISPR Gene Editing")
Targeted Delivery – A Holy Grail For CRISPR Gene EditingPrecise CRISPR delivery remains the bottleneck to safer, more potent gene editing. Advances in LNP design, targeting strategies, and extrahepatic delivery are redefining what’s possible in vivo.
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![Ribosome, biological cell constructing mRNA molecule-GettyImages-1352440366]( "The Hidden Physics Of RNA-LNPs: Tuning RNA Encapsulation For Potency And Safety")
The Hidden Physics Of RNA-LNPs: Tuning RNA Encapsulation For Potency And SafetyWhy LNPs that look identical behave differently in cells. This piece reveals how mixing physics and payload uniformity shape RNA potency, safety, dosing, and manufacturability—beyond size alone.
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![data business analysis, Data Management System, metrics-GettyImages-1480239160]( "Benchmarking RNA Delivery Performance: Toward Standardized Metrics For Translational Success")
Benchmarking RNA Delivery Performance: Toward Standardized Metrics For Translational SuccessAs RNA pipelines mature, delivery success demands shared benchmarks. This article proposes standardized, stage-specific metrics to compare platforms, guide optimization, and strengthen regulatory confidence.
FORMULATION VIDEOS
Unlock next-generation nanoparticle and LNP manufacturing. Achieve high throughput, minimal waste, and superior quality with a compact, automated, and contamination-controlled system.
Three LNP experts from Sanofi, Hopewell Therapeutics, and BioNTech collectively discuss how far we’ve come in understanding the structure of our LNPs while also shedding light on the variables that have the greatest potential of causing shifts in our products’ structure/function.
In this Advancing RNA Live clip, CMC Consultant Sujit Jain explains the numerous ways that adding targeting ligands “stress tests” the standard LNP manufacturing platform, as well as outlines which capabilities are most important for companies to consider when selecting an outsourcing partner for their active delivery strategies.
Explore how lipid nanoparticles are driving breakthroughs in cell therapy, from mRNA-based immune cell engineering to genome editing for CAR T cells and HSPCs from leading experts.
ARTICLES, APP NOTES, CASE STUDIES, & WHITE PAPERS
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![GettyImages-1327112218 Scientist using a laptop in a laboratory]( "Tackling Antimicrobial Resistance")
Learn how three companies collaborated to develop a new antibiotic to address the increasing development of antimicrobial resistance (AMR) that threatens the global health landscape.
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![Nova Benchtop]( "Transferring From Microfluidics To A Turbulent Mixer")
What solutions did the client featured in this case study find when they sought help in transferring their formulation process to a turbulent Impinged Jet Mixing (IJM)?
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![Gibco sampler]( "The Value Of Premium Gibco Peptones")
Achieve the optimal nutritional balance with diverse supplements tailored for your specific bioprocess that can be added to maintain a nutritionally balanced medium.
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![iStock-1140779660-drug-development-lab]( "Enabling Continuous Manufacturing For CAR-T And LNP-Based Therapies")
Breakthrough therapies are challenged by complex, batch-based manufacturing. A novel, integrated system enables continuous processing, improving consistency and reducing manual handling for advanced modalities.
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![mRNA GettyImages-1356994684]( "Freezing mRNA: Best Practice")
By following some of the best practices in freezing mRNA, you can effectively balance product quality, cost-effectiveness, process safety, and efficiency.
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![GettyImages-533059254-rna-dna-strand-light]( "Scalable, Sustainable Support For Next‑Gen Primer Systems")
Explore how an optimized solid‑support design enables higher synthesis scales, steadier pressures, and lower solvent use while preserving yield and purity across diverse oligonucleotide lengths.
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![Evonik1]( "How mRNA Technology Is Shaping The Future Of Medicine")
Discover how mRNA technologies open the doors to a whole range of new gene therapies and the role of lipid nanoparticles (LNPs) in current and future developments.
