RNA Formulation Articles

1. The Hidden Language Of RNA: How lncRNA-Splicing Networks Are Redefining The Future Of Therapeutics 6/19/2026

   Long non-coding RNAs and splicing networks are emerging as master regulators of cellular identity, opening new therapeutic opportunities beyond proteins.

2. RNA-Binding Proteins As Architects Of Post-Transcriptional Control In Disease Biology 6/18/2026

   RNA-binding proteins orchestrate splicing, stability, localization, and translation, emerging as powerful regulators and therapeutic targets in disease.

3. Targeting The Uncharted Heart: Why The Next Era Of siRNA Belongs In Cardiology 6/15/2026

   During our conversation, Gallagher walked me through what’s keeping her up at night as she leads the company and its first siRNA candidate toward an IND, elaborating on the role RNA can play in cardiomyopathies and identifying the unique challenges of developing RNA medicines today.

4. Structure-Guided siRNA Design: How Chemistry, Context, And Constraint Are Shaping The Next Phase Of RNAi Therapeutics 6/8/2026

   As siRNA design matures, the next breakthroughs will depend on balancing chemical optimization, delivery challenges, and expanding beyond established design rules.

5. Following The Data To The Heart: Atrium's Quest For Next-Gen Targeted RNA Delivery 6/8/2026

   In this two-part series, Gallagher shares more about her goals for Atrium following its spin-out from Novartis, articulating what it looks like and means to “pave a path” to greater patient access in rare cardiomyopathies. Here in part one, we start with a look into the formation of Atrium, sharing the “why” behind the company’s formation and what’s next for the company’s targeted delivery platform. 

6. Scaling RNA Therapeutics: Purification, LNP Formulation, And GMP Manufacturing (Pt. 2) 6/4/2026

   Part 2 explores the downstream technologies that turn RNA into a therapeutic product, from impurity removal and LNP formulation to GMP infrastructure and scalable manufacturing.

7. From Exosomes To Nanodrugs: Advancing Therapeutic Delivery For CNS Repair 6/1/2026

   Exosomes are biological vesicles used for cellular communication that can overcome CNS barriers, delivering therapeutic cargo for CNS and optic nerve injuries.

8. Why RNAi-Based Oncology Must Move Beyond Single-Target Thinking 5/29/2026

   RNAi therapeutics may help oncology move beyond single-target drugs by disrupting adaptive tumor survival networks driving resistance in solid tumors.

9. What Makes An RNA Platform Investable? Lessons From The Last Wave Of Biotech Financing 5/28/2026

   RNA investing has shifted from hype to scalability, forcing companies to prove manufacturability, delivery strength, and platform-wide value.

10. Beyond Hairpins: A New Translational Repression Assay Expands RNA-Binding Protein Research 5/26/2026

    Researchers expanded translational repression assays beyond RNA hairpins, enabling scalable study of linear RNA-protein interactions in living cells.