RNA Formulation Solutions

  1. GenVoy-ILM™ T Cell Kit For mRNA, Ignite™ 7/1/2022

    GenVoy-ILM™ T Cell Kit for mRNA, Ignite is an lipid nanoparticle (LNP) reagent mix optimized for the delivery of messenger RNA (mRNA) or Cas9 mRNA/sgRNA into activated human primary T cells.

  2. Accelerating Gene Therapy With The HIT SCAN Platform 4/7/2025

    Battelle’s HIT SCAN™ platform accelerates gene therapy by using high-throughput methods to design, screen, and optimize polymer nanoparticles (PNPs) for effective, non-viral delivery.

     

  3. mRNA/LNP Development And Manufacturing Services

    Messenger RNAs (mRNAs) represent a fast-emerging class of biotherapeutics. In recent years, we at Lonza have amassed considerable expertise in the commercial manufacturing of mRNA and its encapsulation in Lipid Nanoparticles (LNP) at cGMP quality.

  4. Cleanrooms And Equipment For mRNA Drug Manufacturing 6/9/2023

    Revolutionizing Global mRNA Production: Germfree's Innovative Cleanrooms Drive Manufacturing Success

    Cleanroom requirements for mRNA manufacturing encompass stringent particle control, temperature and humidity management, solvent management and robust contamination prevention strategies. Germfree’s advanced cleanroom solutions address these challenges, ensuring seamless equipment integration, process adaptability, and compliance with regulatory standards. Their tailored mobile and modular facilities support the emerging trend for localized vaccine production, empowering biopharmaceutical companies to harness the transformative potential of mRNA technology in a rapidly advancing field, and ultimately contributing to global immunization efforts.

  5. Non-Viral Gene Delivery (NVGD) Using Polymeric-Nano Particles

    Examine a NVGD platform that tackles the primary obstacle hindering gene editing therapies: efficient delivery. Utilizing engineered nanoparticles, the platform overcomes limitations associated with payload size.

  6. Metabolite And Lipid Analysis Service 10/29/2024

    Unlock actionable insights into your cell culture process with metabolite and lipid analysis, enabling data-driven optimizations for growth, titer, and product quality.

  7. Single-Use System For Clinical And Commercial Production Of LNPs 7/21/2023

    Learn about a scalable, single-use platform with built-in automation and regulatory compliance that enables standardized manufacturing workflows for mRNA-LNP drug product production.

  8. Non-Viral In Vivo Transfection - Cationic Lipids For LNP Formulation 7/13/2023

    LipidBrick® IM21.7c

    •  Efficient: Modulates LNP properties to adapt the biodistribution depending on the therapeutic purpose
    •  Secure: Use a unique lipid structure protected by an independent patent owned by Polyplus®
    •  Accelerate your project: in vitro and in vivo proof of concept have been successfully performed
  9. Leveraging Transformational Formulation Technologies: LNPs 2/16/2023

    Increasingly we are seeing customers that are looking for specialized formulation capabilities and, specifically, expertise in developing lipid nanoparticles. August Bio can work with a range of LNP formulation and sizing technologies to achieve the desired product profile.

  10. in vivo mRNA Delivery Using Liposome-Based Reagent 12/12/2022

    in vivo-jetRNA®+ is a ready-to-use reagent that does not require formulation equipment that leads to 100% mRNA encapsulation leading to efficient mRNA delivery.