RNA Formulation Resources

  1. Reducing Risk In mRNA Therapeutic Development 8/12/2024

    Advancements in purification, delivery mechanisms, and stability during storage and transport will enable the future of mRNA-based therapies.

  2. Transfection Solutions For Highly Reliable And Effective Gene Silencing With siRNA And Co. 2/4/2022

    We discuss the process of transfection and highlight two highly effective vectors for both in vitro and in vivo gene therapy applications.

  3. The Paradigm Shift: From Scale-Up To Scale-Out In Genetic Medicine 2/18/2025

    The shift from "scale-up" to "scale-out" in genetic medicine enhances production speed, revolutionizing pharmaceutical manufacturing and accelerating life-saving therapies for global patient populations.

  4. Targeted LC-MS/MS Detection Of Lipid Impurities In Lipid Nanoparticles 12/9/2024

    Learn about an HPLC-MS/MS method for detecting lipid impurities in lipid nanoparticles (LNPs) and why it is critical for quality control of LNP-based drug delivery systems.

  5. Where Can Novel Non-Viral Polymeric Delivery Agents Take Us? 1/18/2023

    Explore ongoing work to harness different types of HDR templates in order to build cutting-edge systems with the potential to enable point-of-care cell and gene therapy manufacture.

  6. Formulation Process And Analytical Development Capabilities 3/25/2024

    Explore process and analytical development capabilities that can help you advance your formulation to GMP Manufacturing.

  7. Defining A Process For Your Unique mRNA 3/21/2023

    Define a process for your unique mRNA with this interactive guide to pDNA, mRNA, and LNP. Overcome challenges with solutions that can help you develop a next-generation production strategy.

  8. Analytics And Bioassays Can Safely Fast-Track mRNA-LNP Drug Development 2/23/2023

    One main mRNA technology challenge is the formulation of delivery systems like lipid nanoparticles (LNPs). Learn about evading impurities in lipids, the future of mRNA-based genomic medicines, and more.

  9. Understanding The Microfluidic Platforms For Scaling Nanoparticle Production 10/13/2022

    Learn about the benefits of microfluidics for nanoparticle production over traditional methods as well as scaling nanoparticle production for clinical or industrial use.

  10. Navigating Challenges In Progressing Breakthrough RNA Therapeutics 5/14/2024

    RNA therapeutics hold immense promise for precision treatment, but their development faces challenges. A CDMO with adaptable platforms and flexible timelines can help reduce time and costs.