RNA Formulation Resources

  1. mRNA: Challenges And Strategies Related To The DNA Template Process 2/15/2023

    Encapsulated mRNA–LNP creation begins with synthesizing the DNA template. Explore insights on DNA template synthesis, the challenges and strategies of generating a DNA template using PCR, and more.

  2. Boost LNP Drug Potency With Optimized Delivery Formulations 11/21/2022

    Lipid nanoparticles (LNPs) function as a drug delivery system for nucleic acids. Learn about the biomedical applications of LNPs as well as the anatomy, formulation optimization, and safety of LNPs.

  3. LNP Formulation For mRNA Delivery 2/15/2023

    Microfluidic mixing is one of the most effective means to formulate LNPs for its scalability and reproducibility. Explore LNP formulation, polishing, sterile filtration of mRNA-LNPs, and more.

  4. PEG In LNP Formulations: Addressing Challenges And Seeking Solutions 2/8/2024

    Polyethylene glycol and similar variants have driven innovative research for therapies. However, the continued use of PEG poses significant drawbacks.

  5. The Future Of mRNA: Four Key Focuses For Industry 8/12/2024

    Compared to traditional protein-based therapies, mRNA drugs exhibit unique pharmacokinetic profiles and can be rapidly developed, making overcoming their challenges critical for the industry.

  6. Versatile Lipid Nanoparticle Platform For Efficient Gene Editing 6/3/2025

    Lipid nanoparticles enable efficient gene editing in hard-to-transfect cells like T-cells and blood stem cells, which offers scalable, clinically relevant methods for developing advanced therapies for cancer and rare diseases.

  7. Ready To Amplify Plasmid (pDNA) In Bacteria? 11/14/2023

    Explore how to use and amplify pDNA from the development of recombinant proteins and viral vectors to advanced bio-therapeutics such as mRNA vaccines.

  8. Translation Of RNA Medicines From Design To Clinic 3/2/2022

    Understand the advantages and challenges of lipid-based delivery systems for successful translation of RNA into clinical development.

  9. Navigating Challenges In Progressing Breakthrough RNA Therapeutics 5/14/2024

    RNA therapeutics hold immense promise for precision treatment, but their development faces challenges. A CDMO with adaptable platforms and flexible timelines can help reduce time and costs.

  10. How To Make The Best LNPs 1/22/2024

    There are various factors that require careful consideration throughout the process of formulating LNPs and utilizing them for successful mRNA delivery and translation.