RNA Formulation Resources

1. Analysis Of LNP Lipids With Evaporative Light Scattering Detection 12/6/2024

   Jump into this thorough analysis of lipids in LNP formulations using HPLC, a technique crucial for quality control in the production of mRNA vaccines and therapeutics.

2. Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines 3/24/2025

   Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.

3. mRNA: Challenges And Strategies Related To The DNA Template Process 2/15/2023

   Encapsulated mRNA–LNP creation begins with synthesizing the DNA template. Explore insights on DNA template synthesis, the challenges and strategies of generating a DNA template using PCR, and more.

4. Integrate Cryopreservation Into the End-To-End Supply Chain 5/28/2026

   Cryopreservation should be integrated across the entire supply chain to ensure traceability, reduce risk at handoffs, and support consistent, scalable therapy development and delivery.

5. Mixing Technology: Linear Scalability And Mixing Precision For Nanoparticle Formulation 8/5/2025

   Find out how you can achieve precise control and linear scalability in nanoparticle formulation with mixing technology that minimizes batch-to-batch variability and simplifies the scale-up process.

6. Recommendations For Successful IND Approval Of RNA-LNP Drugs 8/22/2023

   The existing regulatory system is ambiguous for RNA therapeutics. Leverage this Investigational New Drug (IND) guide to help accelerate and strengthen the process IND filing of novel nanomedicines.

7. LNP-Mediated Cell Transfection In Bioreactors Across Workflows 6/24/2026

   Lipid nanoparticles are redefining immune cell engineering. Delve into new data that demonstrates the performance across multiple cell types and bioreactor systems, supporting their potential workflows.

8. Optimizing Lipid Formulations For Targeted RNA-LNP Applications 9/13/2022

   Learn about the considerations and challenges of using ionizable lipids, including the 5 types of lipids used for RNA delivery.

9. Establishing Analytical Methods For mRNA-Based Therapies 6/13/2023

   Here, we provide a detailed description of assays for sequence identification and LNP composition in mRNA-LNP products that support the development of safe and effective mRNA therapies.

10. Scalable, Sustainable Support For Next‑Gen Primer Systems 1/27/2026

    Explore how an optimized solid‑support design enables higher synthesis scales, steadier pressures, and lower solvent use while preserving yield and purity across diverse oligonucleotide lengths.