RNA Formulation Resources

1. A Novel RNA Lipid Nanoparticle Platform: Gene-Edited CAR T Cells For Off-The-Shelf Cancer Therapy 4/14/2022

   We report on the use of a novel lipid nanoparticle (LNP) reagent in a validated protocol to achieve successful complex gene editing in primary T cells with high efficiency while maintaining high cell viability.

2. mRNA Manufacturing And Formulation 11/15/2022

   From fermentation to formulation, mRNA manufacturing requires a toolbox of technologies, services, and expertise. Explore our portfolio of solutions for making, purifying, and formulating mRNA.

3. Lowering The Lipid Barrier To RNA-LNP Therapeutics 8/22/2023

   Industry experts discuss current and future trends, formulating successful lipid compositions and navigating the constantly evolving genomic medicine landscape.

4. Defining A Process For Your Unique mRNA 3/21/2023

   Define a process for your unique mRNA with this interactive guide to pDNA, mRNA, and LNP. Overcome challenges with solutions that can help you develop a next-generation production strategy.

5. Lipid Nanoparticle Compositional Analysis By UHPLC-CAD 6/30/2023

   Explore results generated from an internal study using a proprietary mRNA-LNP formulation and UHPLC-CAD, a powerful technique for the analysis of compounds that do not contain chromophores.

6. Nanoparticle Engineering Addresses The Challenge Of Poor Aqueous Solubility 3/24/2023

   As pharma companies aim to overcome development obstacles, it is important to incorporate GMP expertise alongside novel technologies that can enhance the properties of APIs and dosage forms.

7. How mRNA Technology Engineers Next-Generation Antibodies 4/26/2024

   Monoclonal antibodies (mAbs) stand as pivotal drug products and biochemical reagents in the 21st century. Explore how mRNA-encoded antigens could revolutionize antibody discovery.

8. The Key To Accelerating RNA-LNP Drug Development 12/27/2023

   Learn about the drug development hurdles that must be overcome to deliver on the promise of mRNA.

9. Precision In Nanoparticle Processing And Monodispersed Lipid Nanoparticles For Advanced Therapeutics 11/17/2025

   Precision in nanoparticle processing is key for drug delivery and vaccines. Learn how monodispersed formulations enhance reproducibility and stability for next-generation therapeutics, like RNA-LNPs.

10. Hemophilia - Global Clinical Trial Landscape 11/7/2023

    Delve into the clinical landscape of hemophilia, a rare X-linked congenital bleeding disorder, across three key regions of the globe, namely Asia Pacific, Europe, and North America.