RNA Formulation Videos

1. RNA Vaccine Development To Phase I 4/14/2022

   Dr. John Lewis, Founder and CEO, Entos Pharmaceuticals, presents RNA Vaccine Development to Phase I.

2. RNA-LNP Manufacturing Technology Delivering Transformative Medicines 10/13/2022

   NxGen™ microfluidic technology enables controlled and precise assembly of high-quality, uniform LNPs, ensuring reproducible scale-up of RNA-LNPs while maximizing drug loading and particle quality.

3. Deciphering mRNA Immunogenicity: Early Assessment Of Human Immune Response 6/4/2024

   Review strategies to assess the potential for human immune response following the administration of an mRNA therapeutic, the associated LNP, and the protein encoded for by the mRNA.

4. Simplify CAR-T Cell Manufacturing With LNP-Mediated Delivery 6/3/2025

   Streamline CAR-T cell manufacturing with lipid nanoparticles delivering base editors to create fratricide-resistant, CD45-edited CAR45 T cells, which enables scalable, precise, and potent therapies for blood cancers.

5. Pioneers And Visionaries Of Nucleic Acid And Nanoparticle-Based Therapeutics 12/12/2024

   Explore the future of nucleic acid and nanoparticle-based therapeutics, including mRNA, CRISPR, and gene editing, as experts discuss innovative solutions for complex health challenges.

6. How To Bring Your LNP Formulation To Clinical/Commercial Manufacturing 5/23/2024

   Gain valuable insights into key considerations when selecting lipid excipients for LNP formulations and the process development steps necessary to advance them to GMP manufacturing and clinical trials.

7. Analytical Solutions To Help Accelerate Bioprocessing Success 11/1/2024

   Unlock the power of data-driven bioprocessing. Discover how advanced analytics can optimize your cell culture process, improve performance, and accelerate success.

8. CMC Innovations Worth Watching In The RNA-LNP Space 12/4/2024

   Sanofi’s Sumit Luthra shares several of the analytical and manufacturing innovations/improvements he’s watching and waiting for that will improve our knowledge of LNP composition, structure, function, and quality.

9. CRISPR Meets LNPs: A New Era In Cell And Gene Therapies 7/8/2025

   Explore how lipid nanoparticles are revolutionizing non-viral gene editing with scalable, efficient delivery for both ex vivo and in vivo applications, which features new CRISPR-LNP data in T cells.

10. The State of the Linear mRNA Supply Chain—In Brief

    In this clip, Sanofi’s Greg Troiano kickstarts our discussion on some of the advances he’s seen in the supply chain for linear mRNA-LNP products, both in terms of supply availability and supplier capability.