RNA Formulation Videos

1. Sterilizing-Grade Filtration Of mRNA Encapsulated Lipid-Nanoparticles 9/2/2026

   Compare sterilizing-grade membrane performance at high and low pressures, including throughput, bacterial retention, and the effects of filtration on particle diameter and encapsulation efficiency.

2. A Benchtop System For Lipid Nanoparticle (LNP) Formulation 12/6/2024

   Discover the unparalleled flexibility and automation that sets the IJM NanoScaler Pro apart from other lipid nanoparticle systems.

3. Deciphering mRNA Immunogenicity: Early Assessment Of Human Immune Response 6/4/2024

   Review strategies to assess the potential for human immune response following the administration of an mRNA therapeutic, the associated LNP, and the protein encoded for by the mRNA.

4. Complexity, Biodegradability, And Scale In Active LNP R&D 2/24/2026

   NanoVation Therapeutics’ Dominik Witzigmann and Stealth Co’s John Zuris walk us through the challenges active delivery strategies pose, particularly as it relates to receptor selection, and the emerging technologies/tools that can help us achieve greater delivery specificity to the target cell type.

5. Addressing The Challenges Of LNP Upscaling 11/20/2025

   Overcome LNP upscaling challenges by leveraging fluid mechanical principles. Learn how Impingement Jets Mixing achieves reproducible turbulence and consistent LNP quality across all production scales.

6. RNA-LNP Manufacturing Technology Delivering Transformative Medicines 10/13/2022

   NxGen™ microfluidic technology enables controlled and precise assembly of high-quality, uniform LNPs, ensuring reproducible scale-up of RNA-LNPs while maximizing drug loading and particle quality.

7. Five Practical Considerations To Move From Concept To Clinic 12/17/2025

   Learn more about five key factors for advancing targeted in vivo LNP programs, from formulation and targeting strategies to bioanalytical readiness and scalability.

8. Flexible Liquid Nanoparticle (LNP) Systems 12/6/2024

   From research and clinical studies to full-scale production, revolutionize your lipid nanoparticle (LNP) production with flexible and scalable solutions.

9. Tissue Adenosine Distribution-Guided Gene Selection 2/17/2025

   Unlike conventional predictive biomarkers, which often focus on isolated molecular markers, this strategy integrates spatial metabolomics and genomics, providing a multidimensional perspective.

10. mRNA's Future Beyond The COVID Vaccines 11/28/2022

    In this video, Russell Johnson, VP Formulation Research for RVAC Medicines, and Aalok Shah, Director of Formulation & Drug Delivery, Strand Therapeutics, unpack which learnings can be adapted from ASO-LNPs to mRNA/LNPs and from mRNA vaccines to mRNA therapeutics. They also touch upon which learnings cannot be neatly carried over from these previous success stories.