RNA Analytical/Quality Videos

  1. Using ddPCR Technology To Characterize The Poly(A) Tail Content 7/27/2023

    When characterizing 3’ poly(A) tail length and integrity, Droplet Digital PCR technology demonstrates an orthogonal or alternative method to help ensure the quality and consistency of mRNA products.

  2. Validation Of mRNA Concentration Determination 8/20/2023

    mRNA-based therapeutics require comprehensive analytical testing to meet regulatory requirements. Optimize processes and ensure fast and reliable results as you bring your product to market.

  3. The "Golden Idea Of The Platform" & Its Role In mRNA PD 8/22/2024

    Explore how early-stage companies can implement design space and analytical principles that will help us determine the biggest differences between constructs and how close we may be to a true “platform process.”

  4. Streamline Your mRNA Purification Steps 3/4/2025

    Ensure your mRNA's stability and effectiveness post-transcription with advanced filtration and chromatography techniques to enhance purity and recovery, which delivers high-quality mRNA for superior therapeutics and vaccines.

  5. Is QbD Actually Possible In mRNA Development Today? 8/22/2024

    As the panelists of this Advancing RNA LIVE discussion argue, there are several big limitations we face in implementing QBD today for RNA development.

  6. A&M STABTEST Shares QC Analysis Of Oligo Therapeutics 9/20/2022

    Explore best practices for developing a QC method for identification and impurity analysis of oligonucleotides, as well as tips on mitigating risk by using compliant instrumentation and software.

  7. Don't Forget These Important Points When Selecting An RNA CDMO 8/22/2024

    Together, Omega’s Jeff Atkinson & Sail Biomedicines’ Jim Nolan share their perspectives on the health of the linear mRNA and circRNA outsourcing sector.

  8. Development Of A Mitra Tip Extraction Assay Coupled With LC-MSMS 1/15/2025

    Watch this rundown of a novel method for quantifying L-Citrulline, L-Arginine, and L-Argininosuccinic acid using Mitra tip extraction coupled with LC-MS/MS for enhanced accuracy and reproducibility.

  9. Webinar Teaser: LBA Vs. LC-MS 2/6/2025

    Why are so many sponsors shifting from Ligand-Binding Assays (LBA) to Liquid Chromatography-Mass Spectrometry (LC-MS) for large molecule protein analysis?

  10. How Can Sponsors & CDMOs Collaborate On RNA Analytical/Process Development? 8/22/2024

    Having worked on both the innovator and CDMO sides of the industry, Advancing RNA LIVE panelist Khaled Yamout outlines where he sees the greatest weaknesses in these critical sponsor-CDMO partnerships and offers guidance.