RNA Analytical/Quality Videos

  1. Enabling Real-Time Data Through A PAT Integration 11/12/2025

    Explore how Raman models and autosampling tools enable real-time bioprocess control, delivering richer data and automation. Learn how PAT technologies can help close data gaps and support smarter, more efficient biomanufacturing strategies.

  2. RNA Interference - From Single Gene Studies To Whole Genome Screens 11/7/2022

    Endoribonuclease-prepared siRNAs (esiRNAs) are able to overcome the limitations of RNAi. Learn about esiRNAs, their advantages over standard siRNAs, and ways this technology is utilized in different research fields.

  3. 3 Must-Improve Areas in mRNA Process Development 10/15/2025

    In this Advancing RNA Live clip, panelists Stu Sundseth, Marc Wolfgang, and Christian Dohmen each provide their take on the most critical areas for improvement in mRNA process development.

  4. The Evolving CMC Landscape For mRNA-LNPs 2/24/2026

    In this Advancing RNA Live clip, CMC consultant Sujit Jain unpacks the levels of maturity he’s observed in process and analytical development, as well as supply chain. While vaccines and liver-targeting therapeutics boast what we can call a reproducible platform today, targeted LNP therapies introduce a handful of scale-up sensitivities and characterization hurdles.

  5. Is QbD Actually Possible In mRNA Development Today? 8/22/2024

    As the panelists of this Advancing RNA LIVE discussion argue, there are several big limitations we face in implementing QBD today for RNA development.

  6. Master Your mRNA Manufacturing 3/4/2025

    Join pDNA and mRNA specialists as they discuss innovative mRNA manufacturing solutions for your purification challenges, mRNA stability, and overall product quality.

  7. Goldilocks & The Guidances: Finding "Just Right" For RNA Regulations 6/24/2025

    Do we need more specific regulatory guidance for every RNA modality and therapeutic approach? We asked and the Advancing RNA Live audience answered… Here, panelists Tiffany Lucas and Ulrike Jägle address the audience’s responses, as well as share their thoughts on just how prescriptive the future of regulatory guidance for RNA therapeutics approaches could/should be..

  8. The Make-or-Break Quality Attributes of Plasmid DNA 10/15/2025

    We all know that plasmid quality is foundational in dictating the quality of the final mRNA drug substance. In this clip homing in on upstream process considerations, speakers Stu Sundseth (Tune Therapeutics), Marc Wolfgang (Sail Biomedicines), and Christian Dohmen (Ethris) outline some of the most important CQAs for plasmids and the impact they can have on the resulting quality of the mRNA drug substance for linear mRNA. 

  9. LBA Vs. LC-MS: Competing Technologies At A Development Crossroad 2/6/2025

    Watch as bioanalytical experts Shane Karnik, MS, and Matt Hartle, Ph.D., explore why many sponsors are reevaluating the use of LBA for large molecule protein analysis in favor of LC-MS.

  10. The "Golden Idea Of The Platform" & Its Role In mRNA PD 8/22/2024

    Explore how early-stage companies can implement design space and analytical principles that will help us determine the biggest differences between constructs and how close we may be to a true “platform process.”