RNA Analytical/Quality Videos

  1. What Learnings Can mRNA Take From The Oligonucleotide Regulatory Paradigm? 5/10/2024

    ReciBioPharm’s Melanie Cerullo shares where mRNA needs to “catch up” to its oligonucleotide “cousin” molecules and where regulatory differences may be emerging between modalities.

  2. How "Successful" Are Our mRNA-LNP Outsourcing Partnerships Today? 2/10/2025

    In this snippet, panelist Alex Aust (with the help of several live attendee commenters) tackles a particularly tricky question: Are our outsourcing partnerships producing high quality products today, and what are the most common root causes of batch failures?

  3. Validation Of mRNA Concentration Determination 8/20/2023

    mRNA-based therapeutics require comprehensive analytical testing to meet regulatory requirements. Optimize processes and ensure fast and reliable results as you bring your product to market.

  4. Bioinformatics In mRNA Development: Classification And Integration Conundrums 6/24/2025

    As both Advancing RNA Live speakers point out in this segment, the MHRA guidance focuses deeply on the critical role bioinformatics and AI/ML approaches will play in the development of personalized immunotherapies. Here, Eliquent Life Sciences’ Tiffany Lucas and CureVac’s Ulrike Jägle address the biggest challenges they anticipate companies will face in meeting the agencies’ recommendations.

  5. Analyzing COVID-19 Vaccine Purity Using LC-MS Technologies 11/8/2022

    Explore why process-related impurities are a concern in vaccines and present results and learnings from LC-MS analyses of several mRNA- and protein-based vaccines for COVID-19.

  6. Real-Time Protein Titer Measurements: Simple, Automated, And Compact Solution 7/3/2025

    Accelerate your workflow with an automated IgG titer solution. Obtain precise results quickly, enhancing efficiency from process development to manufacturing.

  7. Best Practices In Aseptic Sampling To Improve Quality In Bioprocessing 5/30/2024

    Learn about the key aspects of aseptic sampling, appropriate methods and circumstances to perform sampling, and the impact a platform and sample containers can have on assay results and process dynamics.

  8. CMC Innovations Worth Watching In The RNA-LNP Space 12/4/2024

    Sanofi’s Sumit Luthra shares several of the analytical and manufacturing innovations/improvements he’s watching and waiting for that will improve our knowledge of LNP composition, structure, function, and quality.

  9. Is QbD Actually Possible In mRNA Development Today? 8/22/2024

    As the panelists of this Advancing RNA LIVE discussion argue, there are several big limitations we face in implementing QBD today for RNA development.

  10. Master mRNA Manufacturing, Purification, And Plasmid DNA Processes 3/12/2025

    Whether you're a pro or a beginner, revolutionize your process and achieve excellence today by enhancing your mRNA manufacturing skills with valuable insights and tools.