RNA Analytical/Quality Videos

  1. Advancing Peptide Characterization Of Critical Quality Attributes With MMS 11/12/2025

    Axxium uncovered hidden peptide aggregation using MMS technology, revealing process-related potency issues missed by conventional methods. Learn how advanced structural analysis can strengthen quality control and biologics development.

  2. What Does 2025 (And Beyond) Hold For The RNA-LNP Space? 12/4/2024

    Three LNP experts share their thoughts on the incremental advancements they’d like to see the RNA-LNP space make in the next few years.

  3. Must-Have CDMO Capabilities And MSA Make-Or-Breaks For mRNA-LNP Outsourcing 2/10/2025

    Three Advancing RNA Live panelists share their greatest needs in outsourcing partnerships for mRNA/RNA-LNP products and where sponsors should be the most prescriptive when drafting an MSA with an outsourcing partner.

  4. Is the mRNA Industry Aligned Around LNP CQAs? 6/9/2026

    In this Advancing RNA Live clip, panelists Ilya Shestopalov, Philippe Talaga, and Elaine Peters share their perspectives on how aligned around our DP CQAs we are from a company and regulatory standpoint, and where specifically misalignments are revealing themselves today. 

  5. Determining Fragment Length for Enzymatic Ligation of gRNA 4/29/2026

    Advancing RNA Live panelists Max De Long, Venkat Krishnamurthy and April Sena address two audience questions about the number/length of fragments for enzymatic ligation of gRNA.  

  6. Are We Missing mRNA Drug Substance CQAs? 6/9/2026

    As a field, we’ve been aligned around CQAs for our mRNA drug substances. However, differences in translation between highly similar mRNAs (i.e., (same sequence, same design, different manufacturers) raises the question of whether we’re missing any QAs/CQAs. Here, Advancing RNA Live panelists Elaine Peters and Ilya Shestolapov share their take. 

  7. Unveiling The Biophysics Behind Bio-Layer Interferometry 9/27/2024

    What is Bio-Layer Interferometry (BLI)? Watch to learn about BLI and the advantages of utilizing a proven BLI platform.

  8. Why Current dsRNA Analytics Don't Quite Cut It 10/15/2025

    In this Advancing RNA Live segment, several speakers raise concerns about the industry's ability to accurately measure impurities, particularly dsRNA, arguing that current analytics are insufficient, especially for high-dose therapeutics.

  9. Enabling Real-Time Data Through A PAT Integration 11/12/2025

    Explore how Raman models and autosampling tools enable real-time bioprocess control, delivering richer data and automation. Learn how PAT technologies can help close data gaps and support smarter, more efficient biomanufacturing strategies.

  10. Fermentation, Analytics, & Quality: Plasmid Production Advancements & Challenges for mRNA Development 4/11/2025

    Advancing RNA Live panelists Tyler Goodwin and April Sena start off our latest discussion on technology innovations in mRNA production by surveying the current manufacturing process for plasmid production, highlighting where they’ve seen advancements and what biotechs need to consider to obtain plasmids of the appropriate quality for mRNA production.