RNA Analytical/Quality Videos

  1. CMC Innovations Worth Watching In The RNA-LNP Space 12/4/2024

    Sanofi’s Sumit Luthra shares several of the analytical and manufacturing innovations/improvements he’s watching and waiting for that will improve our knowledge of LNP composition, structure, function, and quality.

  2. Advancing Peptide Characterization Of Critical Quality Attributes With MMS 11/12/2025

    Axxium uncovered hidden peptide aggregation using MMS technology, revealing process-related potency issues missed by conventional methods. Learn how advanced structural analysis can strengthen quality control and biologics development.

  3. Bioinformatics In mRNA Development: Classification And Integration Conundrums 6/24/2025

    As both Advancing RNA Live speakers point out in this segment, the MHRA guidance focuses deeply on the critical role bioinformatics and AI/ML approaches will play in the development of personalized immunotherapies. Here, Eliquent Life Sciences’ Tiffany Lucas and CureVac’s Ulrike Jägle address the biggest challenges they anticipate companies will face in meeting the agencies’ recommendations.

  4. The Pre-IND "Diaries": What Can mRNA Makers Expect From Early FDA Engagement? 5/10/2024

    Nutcracker Therapeutics’ Oreanna Thomas shares her takeaways from a pre-IND meeting for one of the company’s mRNA therapeutic candidates.

  5. Real-Time Protein Titer Measurements: Simple, Automated, And Compact Solution 7/3/2025

    Accelerate your workflow with an automated IgG titer solution. Obtain precise results quickly, enhancing efficiency from process development to manufacturing.

  6. Addressing The Challenges Of LNP Upscaling 11/20/2025

    Overcome LNP upscaling challenges by leveraging fluid mechanical principles. Learn how Impingement Jets Mixing achieves reproducible turbulence and consistent LNP quality across all production scales.

  7. Purification Of DNA Oligonucleotides Using AEX Chromatography Webcast 4/25/2023

    Explore impurities removed by strong anion exchange chromatography for the advancement of these molecules as therapeutics and a cost-effective, efficient, and scalable purification method.

  8. Best Practices In Aseptic Sampling To Improve Quality In Bioprocessing 5/30/2024

    Learn about the key aspects of aseptic sampling, appropriate methods and circumstances to perform sampling, and the impact a platform and sample containers can have on assay results and process dynamics.

  9. Goldilocks & The Guidances: Finding "Just Right" For RNA Regulations 6/24/2025

    Do we need more specific regulatory guidance for every RNA modality and therapeutic approach? We asked and the Advancing RNA Live audience answered… Here, panelists Tiffany Lucas and Ulrike Jägle address the audience’s responses, as well as share their thoughts on just how prescriptive the future of regulatory guidance for RNA therapeutics approaches could/should be..

  10. Advancements In LNP CMC: What Are The Current "Known Knowns"? 12/4/2024

    In this Advancing RNA Live clip, Sanofi’s Sumit Luthra highlights the learnings we’ve made to-date about how our processes — both in terms of unit operations and process conditions — inform our LNP composition/heterogeneity.