RNA Analytical Quality/Resources
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From Data To Decisions: Accelerating Your mRNA Drug Development With Analytics
11/20/2024
To stay ahead in the competitive landscape of mRNA development, adopt a comprehensive QC strategy today and begin conducting meaningful tests to ensure the quality of your test articles.
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Mastering mRNA Manufacturing: A Focus on Raw Materials & Supply Assurance
10/23/2024
Rapid advancements in mRNA-based therapeutic development have underscored the role of raw material quality and supply chain management in ensuring their successful production.
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Understanding RNA Higher-Order Structure Dynamics For CRISPR Applications
5/5/2025
Scientists are gaining valuable knowledge about the structural dynamics of guide RNAs used in CRISPR-Cas9. This deeper understanding could pave the way for improved gene editing tools.
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Selection And Evaluation Of Hybridization Capture Probes For LC/MS Analysis Of Oligonucleotides
4/23/2025
To overcome challenges in oligonucleotide LC/MS bioanalysis, consider optimizing probe design by evaluating alternative chemistries like PNA for improved recovery and chromatographic performance.
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Optimizing mRNA For Success: A Guide To Enhanced Stability, Delivery, And Efficacy
6/11/2024
RNA offers exciting potential for vaccines, gene therapies, and personalized medicine, but challenges related to stability, delivery, and manufacturing persist.
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Probing RNA Base Pairing And Ligand Interactions In Solution With Infrared-Based MMS
2/21/2025
Discover why Microfluidic Modulation Spectroscopy (MMS) is a novel, label-free, solution-based infrared technique for probing RNA base pairing and ligand interactions.
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Reduce Contamination Risks When Storing Synthetic DNA
10/30/2023
An alternative to traditional polyethylene bags is offering cell and gene therapy manufacturers a solution to contamination concerns regarding DNA or RNA fragments.
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Determining RNA Integrity And Purity By Capillary Gel Electrophoresis
6/30/2023
To ensure mRNA product quality, it's important to confirm the integrity of the RNA. Examine the results of a study challenging the performance of the CGE method in assessing mRNA integrity and purity.
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The Value Of Peptones For Enhancing Biopharmaceutical Productivity
11/18/2024
Peptones, versatile media additives derived from various sources, offer numerous benefits for biopharmaceutical production.
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Engineering The Next Generation Of Lipid Nanoparticles For Advanced Therapeutics
6/10/2025
Lipid nanoparticles (LNPs) face significant hurdles in clinical use due to challenges with their stability, manufacturing, and understanding how their complex characteristics impact therapeutic efficacy and safety.