RNA Analytical Quality/Resources

1. CRISPR sgRNA For Successful Gene Editing: Discovery To Clinic 9/25/2023

   The single guide RNA (sgRNA) is one of the key components of successful CRISPR gene editing. Here we cover all the important aspects of sgRNA and Synthego’s sgRNA products.

2. Leveraging Filtration Plates To Accelerate The Detection Of Vitamin B6 In Clinical Samples For Research Purposes 6/9/2022

   By employing a simple strategy many different lab protocols where filtration is required can be accelerated. Learn more about automation-friendly 96-well filter plates that enable more samples to be filtered in one go.

3. A&M STABTEST Expands Service Offerings In Protein And Oligonucleotide Analysis With LC-MS System 2/22/2022

   CRO upgrades systems to provide regulatory compliance for large-molecule protein analysis, expanding their oligonucleotides capabilities.

4. Quantification Of Large Oligonucleotides Using High Resolution MS/MS 3/4/2022

   Explore how to achieve sensitive, high-resolution analysis of large oligonucleotides, with the opportunity to perform both qualitative and quantitative analysis in a single run.

5. The Value Of Peptones For Enhancing Biopharmaceutical Productivity 11/18/2024

   Peptones, versatile media additives derived from various sources, offer numerous benefits for biopharmaceutical production.

6. Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines 3/24/2025

   Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.

7. Ultra-Sensitive Assay For Anti-Sense Oligonucleotide Quantification 3/1/2022

   Learn about a new level in sensitivity for challenging analytes in matrix that opens doors for accurate bioanalysis and metabolism studies with specificity not achievable with orthogonal methods.

8. Biopharma Production And Quality Control With Electrophoresis 2/20/2025

   Discover how Kaneka Eurogentec, a leading provider of custom DNA synthesis and molecular biology services, enhanced their fragment analysis to achieve higher efficiency and accuracy in their workflows.

9. Methods for mRNA Poly(A) Sizing 4/26/2024

   This study used Oxford Nanopore Technologies' Direct RNA Sequencing Kit and obtained successful sizing of poly(A) tail regions. The results are presented in a histogram and table format.

10. Limiting Off-Target Effects Of CRISPR-Based Products 2/11/2025

    Find out how to enhance CRISPR gene editing specificity by using Next Generation Sequencing to improve sgRNA quality control, addressing off-target effects and ensuring higher sequence fidelity.