RNA Manufacturing Resources

  1. Fit-For-Purpose Lipids Can Accelerate, Scale, And Improve RNA-LNP Drugs 6/22/2023

    Emerging biotech companies are investing in novel delivery capabilities to address different modalities' needs and extra-hepatic delivery. Explore steps to accelerate commercial nanomedicine delivery.

  2. Discussing mRNA: Challenges And Opportunities For Scale-Out And Optimization 2/6/2024

    In a recent Cell & Gene Live event, experts explored challenges surrounding raw materials – both quality and supply – as well as the importance of achieving more efficient scale-out and turnaround times for mRNA production.

  3. A Scalable Single-Use Two-Step pDNA Purification Process 3/6/2024

    Evaluate the performance of a single-use two-step plasmid purification process, and see how it compares to the existing three-step purification method.

  4. Add mRNA Capacity — Flexibly

    Learn about a platform that addresses five critical pain points to help mRNA manufacturers flexibly scale while improving the digital maturity of their sites.

  5. Unlocking New Possibilities For Treating Rare Genetic Diseases 1/15/2025

    With over 7,000 rare diseases, the potential for nanomedicine to revolutionize treatment is immense. While polymer nanoparticles hold great promise, several challenges remain.

  6. Sample Quality Control In Next-Generation Sequencing Workflows 3/4/2026

    See how automated electrophoresis and key integrity metrics strengthen NGS workflows by improving sample assessment, streamlining QC steps, and supporting confident decisions.

  7. Fast Track RNA-LNP Drug Development By Lowering The Lipid Barrier 8/21/2023

    Fast-track RNA-LNP development, streamline screening with off-the-shelf ionizable lipid mixes, and utilize validation strategies to generate reproducible and scalable LNPs for lead candidates.

  8. 5 Areas To Focus Your QRM Strategy For Sterile Drug Products 4/24/2024

    Explore five areas that can form part of a quality risk management strategy to ensure the compliant manufacturing of sterile drug products.

  9. Modeling The Economics Of Vaccine Manufacturing 5/26/2023

    Here, we describe the use of a custom-designed cost model to explore the economics of vaccine manufacturing when using different modalities.

  10. Downstream Process For Gene Therapy, Plasmid-DNA Vaccine Development 6/10/2021

    A guide to plasmid DNA downstream process development including clarification, TFF, chromatography, and sterile filtration unit operations.