RNA Manufacturing Resources

  1. Optimizing Process Efficiency In Upstream Manufacturing 2/8/2019

    Increasing the integration of upstream and downstream processing and moving toward increased automation results in greater optimization of process efficiency — a key goal for biopharma production.

  2. Optimized Performance Model For Yield And Quality Of The mRNA Product 4/9/2024

    Optimize your mRNA production by identifying an optimum set of conditions for the IVT reaction that produces high-quality mRNA in high yield using a design of experiment (DoE) approach.

  3. The Identification Of A MicroRNA With A Key Role In Parkinson's Disease 7/14/2022

    Learn more about the potential of microRNAs as therapeutic targets being investigated for a number of different disease states.

  4. Cell And Virus Banking In OV Development And Manufacturing 5/14/2024

    Delve into the exciting potential of OVs, including the critical role of cell and virus seed banks, and discover key considerations for establishing cell and virus banks for OV production.

  5. Identifying Sustainable Pathways Toward Oligonucleotide Therapeutics

    What sustainable manufacturing processes best address Oligonucleotide environmental impact while maintaining scalability?

  6. Quantification Of Large Oligonucleotides Using High Resolution MS/MS 3/4/2022

    Explore how to achieve sensitive, high-resolution analysis of large oligonucleotides, with the opportunity to perform both qualitative and quantitative analysis in a single run.

  7. How Nanoparticle Platforms Are Unlocking Genetic Medicine's Potential 4/1/2025

    Explore how the HIT SCAN platform accelerates gene therapy delivery by screening polymeric nanoparticles, enhancing precision and regulatory pathways for next-generation genetic medicines.

  8. Standardization And Flexibility In Aseptic Filling

    Standardization and flexibility in aseptic filling were thought to be mutually exclusive. But what if there was a standardized system with flexibility built into the aseptic process, so you didn’t have to choose?

  9. The Sponsor's Clinical Development Handbook For Gene Therapy Trials 6/21/2024

    Gene therapy has existed for decades, but the field is not as mature as it may seem. Here, the author provides essential insights and strategies for overcoming gene therapy development challenges.

  10. mRNA Manufacturing: Overcoming CMC Development Challenges 6/15/2022

    A lack of standardization and cost-effective techniques for manufacturing and analytics for product characterization create CMC challenges for mRNA-based products.