RNA Manufacturing Resources

  1. Ultra-Sensitive Assay For Anti-Sense Oligonucleotide Quantification 3/1/2022

    Learn about a new level in sensitivity for challenging analytes in matrix that opens doors for accurate bioanalysis and metabolism studies with specificity not achievable with orthogonal methods.

  2. Modeling The Economics Of Vaccine Manufacturing 5/26/2023

    Here, we describe the use of a custom-designed cost model to explore the economics of vaccine manufacturing when using different modalities.

  3. mRNA Manufacturing Workflow: Get To Clinic And Market Faster

    Explore each intertwined step in the mRNA manufacturing process and how a flexible approach can get your mRNA product to clinic and market faster.

  4. Cell And Virus Banking In OV Development And Manufacturing 5/14/2024

    Delve into the exciting potential of OVs, including the critical role of cell and virus seed banks, and discover key considerations for establishing cell and virus banks for OV production.

  5. Addressing Challenges In mRNA Drug Development And Manufacturing

    mRNA-based drug products serve as an ideal platform for use in infectious disease, protein replacement, and immuno-oncology applications due to the simplicity of manufacturing and robust immune response.

  6. Developing Robust mRNA Processes In A cGMP Environment 2/17/2023

    Explore current and emerging technologies to optimize mRNA manufacturing, especially when considering commercial production and the validation of processes in a cGMP environment.

  7. Rapid Separation Of Circular RNA Using An mRNA Analysis Kit 8/11/2023

    Achieve high-resolution separation of circular RNA (circRNA) species from linear RNA products, and detect impurities present at 0.1% of that main product, using an mRNA analysis kit.

  8. Scale-Up And Manufacturing Of Self-Amplifying RNA-LNPs 4/18/2022

    This poster shows the work to scale up COVID-19 self-amplifying RNA-Lipid nanoparticle using PNI developed ionizable lipid and formulation from 0.2, to 50 mg scale using PNI’s Manufacturing Platform.

  9. Dancing In The Bioprocessing Ballroom: Voices Of Experience 12/7/2018

    Single-use technology is well-established and made its way into commercial licensed facilities, but there is more innovation in this field which will enhance its versatility into new markets and technologies.

  10. Future Proof Your Process Scale Workflow 3/4/2024

    Discover how you can future-proof your process scale workflow, from starting bases to tangential flow filtration.