RNA Manufacturing Resources

  1. 3 Services Your Biopharmaceutical Supply Chain Partner Should Offer 5/31/2023

    Finding an experienced partner dedicated to reducing risk of contamination and capable of growing with you as project advances through clinical trial stages is essential.

  2. Choosing A CDMO That Can Grow With A Viral Program 10/21/2026

    Viral modalities demand more from CDMO selection: relevant experience, rigorous tech transfer, analytical readiness, and a clear path to scale matter more than equipment alone.

  3. Residual Plasmid Quantification In Gene Therapy Manufacturing Workflows 6/7/2024

    This article details the design and application of a Plasmid DNA - Kanamycin Resistance Gene (pDNA-KanR) kit for residual plasmid quantification in gene therapy manufacturing.

  4. The Sponsor's Clinical Development Handbook For Gene Therapy Trials 6/21/2024

    Gene therapy has existed for decades, but the field is not as mature as it may seem. Here, the author provides essential insights and strategies for overcoming gene therapy development challenges.

  5. The Crucial Role Of Downstream Processing In Optimizing RNA-LNP Drug Development 8/28/2024

    Explore the key aspects of lipid nanoparticle (LNP) development, including the essential downstream processes of Tangential Flow Filtration (TFF) and normal flow filtration.

  6. Optimizing Lipid Formulations For Targeted RNA-LNP Applications 9/13/2022

    Learn about the considerations and challenges of using ionizable lipids, including the 5 types of lipids used for RNA delivery.

  7. Accelerated Development Of Self-Amplifying mRNA (saRNA) Vaccines Using Microfluidics 4/14/2022

    We showcased the utility of microfluidics to enable low shear, rapid screening of preclinical candidates and the swift advancement to GMP-enabling studies.

  8. The Paradigm Shift: From Scale-Up To Scale-Out In Genetic Medicine 2/18/2025

    The shift from "scale-up" to "scale-out" in genetic medicine enhances production speed, revolutionizing pharmaceutical manufacturing and accelerating life-saving therapies for global patient populations.

  9. Designing Agile Manufacturing With An Integrated Drug Product Ecosystem

    Companies aiming to accelerate biomanufacturing operations and use resources efficiently need access to technologies that can safely and efficiently complete their workflow from discovery to delivery.

  10. Starting Smart: Building Early CGT Supply Chains 6/26/2025

    Discover how building a scalable, compliant supply chain can set your CGT program up for long-term success and avoid risks that could derail progress down the line.