RNA Manufacturing Resources

  1. Exploring Osmolality As A CQA Within RNA Therapeutics 10/3/2023

    Discover how osmolality can be applied throughout the bioprocessing workflow for RNA, and recognize the importance of this sensitive measurement, from formulation optimization to cryopreservation techniques.

  2. Developing A HIC Polishing Step For The Removal Of mAb Aggregates 9/28/2023

    Learn in-depth about the development of a flow-through polishing step that employs hydrophobic interaction chromatography for the elimination of monoclonal antibody aggregates.

  3. GMP Manufacturing Facility For Viral Vector Production 3/27/2018

    A new GMP production facility for viral vectors from nonadherent cell cultures alleviates concerns that there will be a restriction of speed in getting viral vector products from the laboratory to the patient.

  4. Oligonucleotide Manufacturing: Take Control Of Your Process

    What do you need to know before you take your process in-house? A team of experts on nucleic acids therapeutics outlined five key things for you to consider as you make the change.

  5. The Value Of Peptones For Enhancing Biopharmaceutical Productivity 11/18/2024

    Peptones, versatile media additives derived from various sources, offer numerous benefits for biopharmaceutical production.

  6. mRNA Process And Cost Modeling: A Tool To Optimize Process Development

    Demand for mRNA-based medicine production continues to increase, as do investments in prophylactic and therapeutic indications. Explore a cost-model that compares all modalities.

  7. Efficient, Scalable Purification Of mRNA By Affinity Chromatography 6/7/2021

    Increasing demand for mRNA as a therapeutic product requires efficient, scalable purification methods. Here, a monolithic stationary phase is used to purify mRNA from a capping mix of Luc2 RNA.

  8. mRNA/saRNA Manufacturing - RNA Therapeutic Delivery And Applications 7/11/2023

    Venkata Indurthi, Ph.D., shares his knowledge and experience with manufacturing RNA, including insight into RNA delivery and the applications–present and future–that innovations in the field are enabling.

  9. mRNA Manufacturing Workflow 6/2/2021

    Therapies based on messenger RNA, such as mRNA vaccines, have revolutionary potential. Learn more about key objectives, considerations, and strategies in mRNA manufacturing.

  10. Navigating Challenges In Progressing Breakthrough RNA Therapeutics 5/14/2024

    RNA therapeutics hold immense promise for precision treatment, but their development faces challenges. A CDMO with adaptable platforms and flexible timelines can help reduce time and costs.