RNA Manufacturing Resources

  1. Fit-For-Purpose Lipids Can Accelerate, Scale, And Improve RNA-LNP Drugs 6/22/2023

    Emerging biotech companies are investing in novel delivery capabilities to address different modalities' needs and extra-hepatic delivery. Explore steps to accelerate commercial nanomedicine delivery.

  2. Optimizing Process Efficiency In Upstream Manufacturing 2/8/2019

    Increasing the integration of upstream and downstream processing and moving toward increased automation results in greater optimization of process efficiency — a key goal for biopharma production.

  3. Current Challenges In The Plasmid DNA Manufacturing Process 4/24/2026

    PolyA tail stability shapes mRNA potency, consistency, and manufacturability. Addressing integrity early reduces variability, simplifies workflows, and supports reliable clinical scale‑out.

  4. Effective Environmental Monitoring And Control In Pharma Operations 10/16/2025

    A structured contamination control strategy uses the Plan, Do, Study, Act model, focusing on EMPQ, meticulous planning, trend analysis, and continuous improvement with CAPA and change control.

  5. The Checklist For Evaluating In-Vivo CAR-T Manufacturing Partners 10/16/2026

    Choosing the right in vivo CAR-T manufacturing partner requires looking beyond cost to the capabilities that protect scalability, compliance, safety, and development timelines.

  6. Modeling The Economics Of Vaccine Manufacturing 5/26/2023

    Here, we describe the use of a custom-designed cost model to explore the economics of vaccine manufacturing when using different modalities.

  7. mRNA Research Services To Accelerate Your Project 10/9/2026

    Codon optimization can speed early mRNA and LNP projects by weighing manufacturability, stability, and expression upfront, with research-stage work shaped around the end goal of scalable, low-immunogenicity candidates.

  8. GMP-Source® And Phase-Appropriate Use For Early-Stage Clinical Trials 9/16/2021

    GMP-Source is a more robust, less rigid alternative to full cGMP production that mirrors nearly all of the oversight and quality standards of full cGMP production while relaxing certain commercial standards, helping companies overcome the hurdles that can stall early development.

  9. Rapid Separation Of Circular RNA Using An mRNA Analysis Kit 8/11/2023

    Achieve high-resolution separation of circular RNA (circRNA) species from linear RNA products, and detect impurities present at 0.1% of that main product, using an mRNA analysis kit.

  10. The Evolution Of Nucleotide Production 4/2/2025

    From harsh chemicals to gentle enzymes: Explore the groundbreaking shift in nucleotide synthesis, making drug manufacturing cleaner, greener, and more efficient.