RNA Manufacturing Resources

  1. Levers To Optimize The IVT Reaction For Increased mRNA Yield 2/27/2023

    Learn about tools to optimize the IVT reaction for enhanced mRNA yield, along with how factors such as magnesium ion and nucleotide concentrations significantly impact that IVT reaction performance.

  2. The Value Of Peptones For Enhancing Biopharmaceutical Productivity 11/18/2024

    Peptones, versatile media additives derived from various sources, offer numerous benefits for biopharmaceutical production.

  3. When Is A New Biologic Ready For GMP Production? 1/17/2023

    While there are differences by modality in DNA, RNA, and protein, find general recommendations on questions to prepare for and steps to consider when preparing to move to clinic.

  4. Imagine The Future: Enhanced Oligonucleotide Synthesis 3/4/2024

    Learn about flexible control software that has revolutionized the way method creation, evaluation, and process optimizations for scale-up are completed.

  5. mRNA Manufacturing Workflow: Get To Clinic And Market Faster

    Explore each intertwined step in the mRNA manufacturing process and how a flexible approach can get your mRNA product to clinic and market faster.

  6. Leveraging Single-Use Technology For mRNA-LNP Drug Manufacturing 6/12/2023

    Single-use technology is vital for ensuring the quality and expedited market entry of genomic medicines. Learn how LNP technology is paving the way for a new era of personalized, precise medicine.

  7. Cell And Virus Banking In OV Development And Manufacturing 5/14/2024

    Delve into the exciting potential of OVs, including the critical role of cell and virus seed banks, and discover key considerations for establishing cell and virus banks for OV production.

  8. Communication And Transparency In Secondary Supply Qualification 8/12/2024

    What should you look for when searching for the right vendor to help you maintain security of raw materials and how can you establish communication that builds confidence?

  9. Genome Editing of Human Primary T Cells With Lipid Nanoparticles 4/18/2022

    We show CRISPR/Cas9-mediated knockouts of the T cell receptor and explore multi-step LNP engineering to produce TCRÉ‘β KO CAR T cells, a promising approach towards allogeneic CAR T cell therapy.

  10. Getting Genomic Medicines Ready For Prime Time 2/5/2024

    Explore the benefits of building a manufacturing process early, how research into LNPs in nucleic acid therapeutics will contribute to the development of future drugs, and more.