RNA Manufacturing Resources

  1. Enhanced mAb Production With High-Intensity Perfusion CHO Medium 11/27/2024

    Reach new heights in mAb production with a high-intensity perfusion CHO medium designed to support consistently high product yield and quality in continuous perfusion cultures using CHO-K1 cells.

  2. The Paradigm Shift: From Scale-Up To Scale-Out In Genetic Medicine 2/18/2025

    The shift from "scale-up" to "scale-out" in genetic medicine enhances production speed, revolutionizing pharmaceutical manufacturing and accelerating life-saving therapies for global patient populations.

  3. Closed And Semi-Automated Processing Of CAR T Cells 7/5/2019

    Learn about a robust CAR T-cell manufacturing workflow that can be adapted for cGMP compliance in the commercial production of CAR T-cells.

  4. Future-Proofing mRNA Drug Manufacturing: The Value of Continuous Improvement 4/30/2024

    With so many uncertainties permeating the mRNA market, this largely preclinical industry is still seeking answers on how to reach successful therapeutic development. Identifying optimizations, both sequence-dependent and otherwise, to enhance the manufacturing process is crucial for advancing mRNA product development, which holds vast potential to address a wide range of indications.

  5. mRNA Product Purification Process Strategies 2/15/2023

    Impurities from IVT can induce undesired immune responses and negatively impact translation efficiency. Explore the pros and cons of each option for mRNA purification.

  6. A New Centre For Continuous mRNA Manufacturing 5/14/2024

    Explore how a partnership between academia, regulatory agencies, and manufacturing organizations has the potential to reshape the way we produce and distribute mRNA-based therapies.

  7. Achieve Higher Targeted Concentrations 9/30/2025

    Single-pass TFF streamlines downstream processing by reducing footprint, shear exposure, and hold-up volumes. Learn how this approach is advancing efficiency across therapeutic and vaccine production.

  8. Exosome Isolation By TFF And Size Exclusion Chromatography 3/6/2024

    Here, we demonstrate a scalable workflow for the isolation of exosomes that combines tangential flow filtration for the concentration of exosomes followed by gentle size exclusion chromatography.

  9. Novel Lipid Nanoparticle Delivery Reagent And Manufacturing Workflow 4/18/2022

    We aim to highlight that commercially available LNP reagent mix, GenVoy-ILM, is an accessible and easy-to-use LNP formulation that allows for rapid preclinical development of RNA vaccines.

  10. Depth Filtration Devices For Cell Cultures, Fermentation Broths, And Cell Lysates 3/27/2023

    Typically, devices containing depth media filters offer more efficient filtration. Browse depth filtration products for the downstream processing of cell culture solutions, fermentation broths, and lysates.