RNA Manufacturing Resources

  1. Scalable Purification Of In Vitro Transcribed mRNA 7/18/2023

    Learn about the isolation and purification benefits of a resin that is particularly useful in the manufacturing in vitro transcribed mRNA.

  2. Continuous Nanoparticle Manufacturing For Gene Editing Delivery 9/18/2025

    Messenger RNA-LNPs are a promising strategy for delivering gene-editing components. Learn how a continuous manufacturing platform can address the scalability and reproducibility challenges of this process.

  3. Dancing In The Bioprocessing Ballroom: Voices Of Experience 12/7/2018

    Single-use technology is well-established and made its way into commercial licensed facilities, but there is more innovation in this field which will enhance its versatility into new markets and technologies.

  4. Process Development Considerations For RNA-LNP Therapeutics 9/13/2022

    Here, we highlight three important process considerations across the RNA-LNP manufacturing workflow which includes limit size behavior, in-line dilution and downstream tangential flow filtration (TFF).

  5. Next-Gen Bioprocess Monitoring: Smart Data Management And Analysis 10/14/2020

    A new platform that includes digital technologies/data management, process analytical technologies and intensified processing will drive next generation bioprocessing.

  6. Amgen's Digital Transformation: Link Suppliers' Raw Material Data To Patients 10/19/2018

    Using its Supplier Relationship Excellence program, Amgen opened the lines of communication with suppliers and created a feedback loop where data can be shared to optimize operational performance. 

  7. How Tools And Technologies Bring Advanced Therapies To Market 3/2/2022

    Gain insight into industry trends and the tools to support the development of RNA vaccines and therapeutics.

  8. mRNA-LNP Nucleic Acid Assessment From Distinct Formulations 9/8/2023

    Review a showcase of a high throughput robust analysis for nucleic acid integrity and size assessment of mRNA-LNP samples using a multi-capillary system and purity and integrity analysis kit.

  9. Alternative To Cryobags For Large Volume Cryopreservation 6/6/2019

    This study demonstrates an optimized cooling protocol for cryopreserving large-volume cryovials in a controlled-rate freezer, avoiding the need for liquid nitrogen.

  10. New Filtration Protocols Accelerate Viral Vector Development And Enhance Scale Up To Production 3/15/2022

    Read how filtration technology is optimizing a scalable and GMP-compatible purification process for lentiviral vectors that works effectively from research and development through manufacturing.