RNA Manufacturing Resources

  1. mRNA Synthesis Reagents And Manufacturing 8/14/2023

    As novel mRNA therapies are starting to enter clinical stages of development, Aldevron is providing critical support in a number of ways with specialized products and services.

  2. Tangential Flow Filtration System Coupling To Enhance Solution Offerings 3/1/2023

    Discover a simple, easy, and versatile method for capsule and depth filtration of small volumes that moves research from cell harvest to purification as quickly and efficiently as possible.

  3. High-Throughput Characterization Of RNA 5/9/2022

    How a multi-capillary electrophoresis (CE) system is used to efficiently separate a wide range of RNA-based molecules by size and demonstrates the multiplex capability for RNA characterization.

  4. Review Of mRNA Vaccines & Therapeutics Manufacturing Challenges: Plasmid DNA Manufacturing 6/7/2022

    This review suggests technical remedial options for the production of pDNA and focuses on mRNA synthesis, purification, and encapsulation.

  5. Development Of LNP Formulations Using The KNAUER NanoScaler 12/6/2024

    Lipid nanoparticles (LNPs) offer a robust solution for nucleic acids. The NanoScaler system optimizes this technology, enabling scalable and reproducible LNP formulations for diverse applications.

  6. Fast And Efficient Extraction Of mRNA From IVT Mixtures 6/7/2021

    Here, a fast and efficient way to purify polyadenylated mRNA using affinity chromatography on the CIMmultus® Oligo dT column is presented.

  7. Ensure High Quantity And Quality Of Isolated Bacterial Ribonucleic Acid (RNA) 4/29/2022

    In this scientific brief we evaluate the performance of the the Pall Nucleic acid binding (NAB) Nanosep centrifugal device for nucleic acid isolation.

  8. Addressing Challenges In mRNA Drug Development And Manufacturing

    mRNA-based drug products serve as an ideal platform for use in infectious disease, protein replacement, and immuno-oncology applications due to the simplicity of manufacturing and robust immune response.

  9. Quantification Of Large Oligonucleotides Using High Resolution MS/MS 3/4/2022

    Explore how to achieve sensitive, high-resolution analysis of large oligonucleotides, with the opportunity to perform both qualitative and quantitative analysis in a single run.

  10. Eliminating Antibiotic Resistance Gene Transfer Risks In CGTs 8/14/2023

    Learn about the drawbacks of antibiotic resistance that can cause side effects in patients and how an antibiotic-free approach can ease the burden of regulatory compliance and accelerate development.