RNA Manufacturing Resources

1. Accelerated Development: Gene Therapy Vs. Small Molecule 12/26/2023

   Combined with the inherent difficulty of the chemistry behind gene therapy development, its pace, structure, and funding dynamics are unique among treatment modalities.

2. Future Proof Your Process Scale Workflow 3/4/2024

   Discover how you can future-proof your process scale workflow, from starting bases to tangential flow filtration.

3. Aseptic Filling Solution Enhances Sterility Assurance for Pharma Manufacturer 11/21/2024

   Emergent BioSolutions upgraded its Winnipeg site with the Cytiva SA25 aseptic filling workcell to improve sterility assurance, product flexibility, and regulatory compliance for CGT manufacturing.

4. Addressing And Adapting To Evolving mRNA Market Trends 7/6/2022

   Pierre Catignol and Huisub Lim share their insights on current mRNA market trends, manufacturability, choosing an appropriate CDMO partner, and mRNA technology considerations.

5. A Guide To mRNA Vaccine Production And Manufacturing Services 7/13/2023

   Find out more about the key steps for successful mRNA vaccine production, which encompasses mRNA manufacturing, and ways that you can save valuable time from the start of manufacturing.

6. Host Cell Protein (HCP) Removal Post Virus Inactivation In mAb Processing 2/26/2026

   Clarifying post–virus inactivation streams with a charged depth filter can remove precipitates while significantly reducing HCPs. See how a dual‑layer filtration approach supports stronger impurity control.

7. Pre-Banking And Avoiding Manufacturing Challenges For GMP Plasmids Containing Unstable Sequence Regions 4/21/2021

   Ensuring consistent replication and proper retention of plasmid DNA sequence is vital to the economics and efficiency in generating starting materials used for production of AAV delivered gene therapy and mRNA vaccines and therapeutics.

8. Scaling A mAb Production Process To A Single-Use Platform 9/27/2019

   The transfer of mAb production processes between scales is difficult. In this study, we leveraged existing physical characterization data and scaled a process from microbioreactor to production scale.

9. Cell Therapy Manufacturing: The Supply Chain Challenge 4/1/2019

   Overcoming the challenges of manufacturing and administering a complex product to any patient is critical for delivering cell therapies. Two industry experts detail strategies to meet supply chain challenges.

10. Let The Future Start Today: Development Of Better LNP-Based Genetic Medicines 11/8/2022

    Discover how you can accelerate the time to patients for new vaccines and therapies with innovative, streamlined technology that is quicker and more intuitive.