RNA Manufacturing Resources

1. Avoiding The Pitfalls Of LNPs And Complex Formulations

   Explore the necessary components of a smooth tech transfer for LNP-based drugs, including the variables that impact LNP formulation and the outsourcing strategies needed to avoid common pitfalls.

2. How Outsourcing RNA-LNP Production Can Have A Competitive Advantage 2/23/2023

   Manufacturing RNA-containing LNPs demands specialized expertise  Explore some of the challenges of RNA-LNP drug manufacturing and the advantages of outsourcing RNA-LNP formulations.

3. Understanding The Hidden Value Of Quality 6/26/2023

   Costs of poor quality (COPQ) cannot be overstated. Review the statistics that prove how costly it can be to avoid resolving quality issues in your processes and supply chain.

4. The Execution Stage Of Technology Transfer 5/2/2024

   What are the key elements in the readiness stage of a technology transfer is critical to your success? Explore Process Performance Qualification (PPQ) and the execution stage of PDA TR-65.

5. mRNA/saRNA Manufacturing RNA Analytics And Testing 5/24/2023

   Venkata Indurthi, Ph.D., shares his knowledge and experience with manufacturing RNA, including key downstream considerations for RNA characterization and purity and how optimization can result in more efficient dosing.

6. Drug Discovery And Screening, A Digital Era For RNA-LNP Therapeutics 11/21/2022

   Learn about the key stages of drug discovery and screening as well as how to overcome bottlenecks in screening mRNA-LNPs to rapidly develop genomic medicines.

7. Demand More From Your Oligo Synthesizer 3/4/2024

   The market for oligonucleotide therapeutics is expanding, and the pipeline is diverse. Gain insight into how you can fast-track your molecule's development with verified synthesizers, columns, and scientific support and expertise.

8. mRNA Vaccine Development: Planning, Workflow, Supply Chain Success 5/17/2022

   A review of insights derived from the development of mRNA-based COVID-19 vaccines and how they can be applied to accelerate progress in the manufacture of vaccines and therapeutics moving forward.

9. Sequencing Of Synthetic Oligonucleotides And Their Impurities 9/20/2022

   We demonstrate an automated, compliance-ready liquid chromatography-mass spectrometry (LC-MS) workflow for sequence confirmation of oligonucleotides and their impurities.

10. Fit-For-Purpose Lipids Can Accelerate, Scale, And Improve RNA-LNP Drugs 6/22/2023

    Emerging biotech companies are investing in novel delivery capabilities to address different modalities' needs and extra-hepatic delivery. Explore steps to accelerate commercial nanomedicine delivery.