RNA Manufacturing Resources

1. How Syringe Filtration With Integrated Prefilter Technology Improves HPLC Performance And Throughput 4/29/2022

   In this article we review how particulate removal through filtration effects column life and how to handle difficult to filter samples.

2. Unlocking The Full Potential Of Genomic Medicine 6/1/2022

   There are two key challenges to realizing the potential of genomic medicines, but potential technological solutions are on the horizon, and we examine each.

3. A Scalable Single-Use Two-Step pDNA Purification Process 3/6/2024

   Evaluate the performance of a single-use two-step plasmid purification process, and see how it compares to the existing three-step purification method.

4. Digital Biomanufacturing, Now: From Digital Dreamer To Digital Doer 3/24/2025

   Discover how digital biomanufacturing is revolutionizing drug production by exploring strategies for integrating digital technologies to enhance efficiency and innovation in bioprocessing workflows.

5. Flexibility And High-Quality Extraction Of Genomic DNA And RNA From Yeast, Saccharomyces Cerevisiae 4/29/2022

   In this report, we analyze the quality and quantity of gDNA as well as RNA from S. cerevisiae with Pall NAB Nanosep centrifugal devices in comparison with a renowned commercial brand.

6. New Hope For Neuronal Diseases With Polymer Nanoparticle-Based Gene Therapy 1/28/2025

   A new polymer nanoparticle (PNP) system enables targeted delivery of large genetic payloads to neuronal cells, advancing gene therapies for NF1 and other nervous system disorders.

7. 5 Biggest Trends Of Oligonucleotide Manufacturing In 2022 2/18/2022

   The rapidly growing market for Oligonucleotide manufacturing represents an opportunity for investors and pharma companies that wish to produce novel pharmaceutical products and therapies.

8. Scaling Of Impingement Jets Mixing For LNP Drug Production 12/6/2024

   Delve into the intricacies of Impingement Jets Mixing (IJM) technology and its pivotal role in the scalable and reproducible production of Lipid Nanoparticles (LNPs) for drug delivery.

9. Understanding The Microfluidic Platforms For Scaling Nanoparticle Production 10/13/2022

   Learn about the benefits of microfluidics for nanoparticle production over traditional methods as well as scaling nanoparticle production for clinical or industrial use.

10. Toward A Gene Therapy Platform: What's The Best Format Of TFF? 1/13/2025

    Evaluate tangential flow filtration (TFF) formats and membrane chemistries for AAV gene therapy processing, assessing performance, scalability, economy, and closed processing options.