RNA Formulation Resources

  1. Low-Volume Production For Screening High-Value Nanoparticle Materials 4/18/2022

    A platform that harnesses microfluidic mixing has been demonstrated as a simple, robust, and scalable production method for LNPs encapsulating various types of nucleic acids.

  2. Mechanisms Of LNP-Mediated mRNA Delivery

    Explore the details supporting LNP-mediated mRNA delivery, as well as the challenges facing mRNA based therapeutics in the future.

  3. Achieving Speed And Scale With Optimized Synthesis Solutions 11/15/2023

    Realize optimal coupling efficiency and increase your productivity for oligonucleotide drugs by selecting the right synthesizer and prioritizing automation to define and tweak synthesis methods.

  4. Defining A Process For Your Unique mRNA 3/21/2023

    Define a process for your unique mRNA with this interactive guide to pDNA, mRNA, and LNP. Overcome challenges with solutions that can help you develop a next-generation production strategy.

  5. LNP Formulation For mRNA Delivery 2/15/2023

    Microfluidic mixing is one of the most effective means to formulate LNPs for its scalability and reproducibility. Explore LNP formulation, polishing, sterile filtration of mRNA-LNPs, and more.

  6. Genome Editing Using mRNA-Lipid Nanoparticles For CAR T Cell Therapy 11/22/2023

    Gene delivery platforms must support a diversity of genetic engineering strategies for genomic medicine development. Learn how lipid nanoparticles can accelerate development from discovery to scale-up.

  7. The Importance Of Linear Scalability In Nanoparticle Processing 10/14/2025

    Learn how turbulent jet mixing enables linear scalability, guaranteeing consistent nanoparticle quality from research to commercial production and accelerating product timelines.

  8. Transfection Solutions For Highly Reliable And Effective Gene Silencing With siRNA And Co. 2/4/2022

    We discuss the process of transfection and highlight two highly effective vectors for both in vitro and in vivo gene therapy applications.

  9. Optimized And Scalable LNP Composition For RNA Vaccine Delivery 12/20/2023

    Explore results from a study screening novel LNP formulations for physicochemical attributes, in vitro potency, and in vivo immunogenicity in both SARS-CoV-2 and influenza vaccine applications.

  10. Analytics And Bioassays Can Safely Fast-Track mRNA-LNP Drug Development 2/23/2023

    One main mRNA technology challenge is the formulation of delivery systems like lipid nanoparticles (LNPs). Learn about evading impurities in lipids, the future of mRNA-based genomic medicines, and more.