RNA Formulation Resources

  1. Transfection Solutions For Highly Reliable And Effective Gene Silencing With siRNA And Co. 2/4/2022

    We discuss the process of transfection and highlight two highly effective vectors for both in vitro and in vivo gene therapy applications.

  2. The Future Of mRNA: Four Key Focuses For Industry 8/12/2024

    Compared to traditional protein-based therapies, mRNA drugs exhibit unique pharmacokinetic profiles and can be rapidly developed, making overcoming their challenges critical for the industry.

  3. Analysis Of LNP Lipids With Evaporative Light Scattering Detection 12/6/2024

    Jump into this thorough analysis of lipids in LNP formulations using HPLC, a technique crucial for quality control in the production of mRNA vaccines and therapeutics.

  4. How LNP Technology Meets The Delivery Need Of saRNA Vaccines 6/22/2023

    Explore challenges to the successful development of RNA-based drugs and vaccines as well as the advantages of utilizing lipid nanoparticle technology as a delivery platform for saRNA.

  5. Nanoparticle Engineering Addresses The Challenge Of Poor Aqueous Solubility 3/24/2023

    As pharma companies aim to overcome development obstacles, it is important to incorporate GMP expertise alongside novel technologies that can enhance the properties of APIs and dosage forms.

  6. Freezing mRNA: Best Practice 7/14/2023

    By following some of the best practices in freezing mRNA, you can effectively balance product quality, cost-effectiveness, process safety, and efficiency.

  7. Process Development Considerations For RNA-LNP Therapeutics 9/13/2022

    Here, we highlight three important process considerations across the RNA-LNP manufacturing workflow which includes limit size behavior, in-line dilution and downstream tangential flow filtration (TFF).

  8. Tackling Antimicrobial Resistance 5/14/2024

    Learn how three companies collaborated to develop a new antibiotic to address the increasing development of antimicrobial resistance (AMR) that threatens the global health landscape.

  9. Genome Editing Using mRNA-Lipid Nanoparticles For CAR T Cell Therapy 11/22/2023

    Gene delivery platforms must support a diversity of genetic engineering strategies for genomic medicine development. Learn how lipid nanoparticles can accelerate development from discovery to scale-up.

  10. Cell And Virus Banking In OV Development And Manufacturing 5/14/2024

    Delve into the exciting potential of OVs, including the critical role of cell and virus seed banks, and discover key considerations for establishing cell and virus banks for OV production.