RNA Formulation Resources

  1. Lipid Nanoparticles Boost CRISPR HDR Gene Insertion in Human T Cells 12/12/2025

    Lipid nanoparticles enable precise, non-viral gene editing in T cells to achieve high HDR efficiency and viability in scalable workflows. Explore how this approach overcomes viral vector limitations.

  2. Why Risk Analysis And Lane Qualification Matter 5/28/2026

    Risk analysis and lane qualification show supply chains perform consistently, meeting regulatory expectations by demonstrating control, reducing variability, and ensuring reliable delivery.

  3. Developing A Scalable RNA-LNP Drug Product For Clinical Translation 9/22/2022

    Accelerate essential process development activities with instrumentation solution allowing for highly reproducible and scalable production of RNA-LNPs.

  4. Four Reasons You Should Choose Lyophilization for Your Next Project 12/10/2025

    Lyophilization ensures product stability, extends shelf life, supports sensitive formulations, and simplifies storage and transport, making it a critical choice for modern drug development projects.

  5. Continuous Nanoparticle Manufacturing For Gene Editing Delivery 9/18/2025

    Messenger RNA-LNPs are a promising strategy for delivering gene-editing components. Learn how a continuous manufacturing platform can address the scalability and reproducibility challenges of this process.

  6. Accelerate Efficiency By Decoupling Collection From Manufacturing 6/26/2026

    Cryopreservation eliminates rigid timelines by decoupling collection from production, providing the flexibility needed to optimize facility use and stabilize advanced therapy supply chains.

  7. mRNA: Challenges And Strategies Related To The DNA Template Process 2/15/2023

    Encapsulated mRNA–LNP creation begins with synthesizing the DNA template. Explore insights on DNA template synthesis, the challenges and strategies of generating a DNA template using PCR, and more.

  8. How mRNA Technology Engineers Next-Generation Antibodies 4/26/2024

    Monoclonal antibodies (mAbs) stand as pivotal drug products and biochemical reagents in the 21st century. Explore how mRNA-encoded antigens could revolutionize antibody discovery.

  9. Purification And QC Of An RNA 21‑Mer Oligonucleotide Via LC‑MS 1/27/2026

    Learn how buffer choice, gradient strategy, and pretreatment steps influence recovery, purity, and resolution when purifying a native RNA oligo, with analytical confirmation and practical guidance.

  10. Advancing Cell Therapies With Lipid Nanoparticles 3/24/2025

    Cell therapies, using reprogrammed immune cells, offer innovative treatments for diseases. Discover how lipid nanoparticles (LNPs) enhance these therapies by delivering RNA for gene modulation and next-gen treatments.