RNA Formulation Resources

31. Reducing Risk In mRNA Therapeutic Development 8/12/2024

    Advancements in purification, delivery mechanisms, and stability during storage and transport will enable the future of mRNA-based therapies.

32. Mechanisms Of LNP-Mediated mRNA Delivery

    Explore the details supporting LNP-mediated mRNA delivery, as well as the challenges facing mRNA based therapeutics in the future.

33. Co-Precipitation Of Metal Carbonate Templated Protein Microparticles 12/9/2024

    Explore the automated production of protein microparticles using an innovative method that offers a standardized and scalable solution for co-precipitation in biopolymer particle fabrication.

34. PEG In LNP Formulations: Addressing Challenges And Seeking Solutions 2/8/2024

    Polyethylene glycol and similar variants have driven innovative research for therapies. However, the continued use of PEG poses significant drawbacks.

35. Where Can Novel Non-Viral Polymeric Delivery Agents Take Us? 1/18/2023

    Explore ongoing work to harness different types of HDR templates in order to build cutting-edge systems with the potential to enable point-of-care cell and gene therapy manufacture.

36. Cell And Virus Banking In OV Development And Manufacturing 5/14/2024

    Delve into the exciting potential of OVs, including the critical role of cell and virus seed banks, and discover key considerations for establishing cell and virus banks for OV production.

37. Freezing mRNA: Best Practice 7/14/2023

    By following some of the best practices in freezing mRNA, you can effectively balance product quality, cost-effectiveness, process safety, and efficiency.

38. mRNA-Lipid Nanoparticles Circumvent Viral Vector Limitations 6/1/2022

    Both physical and chemical nonviral gene delivery systems for ex vivo genetic modification offer advantages over viral vectors, including smaller scale production and the low risk of immunogenicity.

39. Scaling Of Impingement Jets Mixing For LNP Drug Production 12/6/2024

    Delve into the intricacies of Impingement Jets Mixing (IJM) technology and its pivotal role in the scalable and reproducible production of Lipid Nanoparticles (LNPs) for drug delivery.

40. High-Throughput Lipid Separation For LNP Formulations 12/6/2024

    Lipid nanoparticles (LNPs) carry immense potential as delivery systems. Learn about the development of isocratic and gradient methods for high-throughput separation of lipids used in LNP formulations.