RNA Formulation Resources

  1. Lipid Nanoparticles Boost CRISPR HDR Gene Insertion in Human T Cells 12/12/2025

    Lipid nanoparticles enable precise, non-viral gene editing in T cells to achieve high HDR efficiency and viability in scalable workflows. Explore how this approach overcomes viral vector limitations.

  2. Unpacking The Importance Of Lipid Nanoparticle Production Platforms 4/15/2024

    Batch processing platforms for LNPs lack efficiency, appropriate controls, and yield optimization. Continuous manufacturing platforms may address some of those issues.

  3. Accelerated Development Of Self-Amplifying mRNA (saRNA) Vaccines Using Microfluidics 4/14/2022

    We showcased the utility of microfluidics to enable low shear, rapid screening of preclinical candidates and the swift advancement to GMP-enabling studies.

  4. Ready To Amplify Plasmid (pDNA) In Bacteria? 11/14/2023

    Explore how to use and amplify pDNA from the development of recombinant proteins and viral vectors to advanced bio-therapeutics such as mRNA vaccines.

  5. Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines 3/24/2025

    Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.

  6. Turbulent Mixing: Scaling Up Nanoparticle Manufacturing For The Future

    Choosing between turbulent and microfluidic mixing methods in your lipid nanoparticle (LNP) production can have a significant impact when scaling up production.

  7. Co-Precipitation Of Metal Carbonate Templated Protein Microparticles 12/9/2024

    Explore the automated production of protein microparticles using an innovative method that offers a standardized and scalable solution for co-precipitation in biopolymer particle fabrication.

  8. mRNA Manufacturing And Formulation 11/15/2022

    From fermentation to formulation, mRNA manufacturing requires a toolbox of technologies, services, and expertise. Explore our portfolio of solutions for making, purifying, and formulating mRNA.

  9. Analytics And Bioassays Can Safely Fast-Track mRNA-LNP Drug Development 2/23/2023

    One main mRNA technology challenge is the formulation of delivery systems like lipid nanoparticles (LNPs). Learn about evading impurities in lipids, the future of mRNA-based genomic medicines, and more.

  10. Scaling Of Impingement Jets Mixing For LNP Drug Production 12/6/2024

    Delve into the intricacies of Impingement Jets Mixing (IJM) technology and its pivotal role in the scalable and reproducible production of Lipid Nanoparticles (LNPs) for drug delivery.