RNA Formulation Resources

1. Novel Lipid Nanoparticle Delivery Reagent And Manufacturing Workflow 4/18/2022

   We aim to highlight that commercially available LNP reagent mix, GenVoy-ILM, is an accessible and easy-to-use LNP formulation that allows for rapid preclinical development of RNA vaccines.

2. Process Development Considerations For RNA-LNP Therapeutics 9/13/2022

   Here, we highlight three important process considerations across the RNA-LNP manufacturing workflow which includes limit size behavior, in-line dilution and downstream tangential flow filtration (TFF).

3. LNP Formulation For mRNA Delivery 2/15/2023

   Microfluidic mixing is one of the most effective means to formulate LNPs for its scalability and reproducibility. Explore LNP formulation, polishing, sterile filtration of mRNA-LNPs, and more.

4. Formulation Process And Analytical Development Capabilities 3/25/2024

   Explore process and analytical development capabilities that can help you advance your formulation to GMP Manufacturing.

5. Laminar And Turbulent Mixing Techniques For LNP Formulations Scale Up 11/4/2025

   Explore the critical factors in scaling up lipid nanoparticle (LNP) formulation, comparing the advantages and limitations of both laminar (microfluidic) and turbulent (tee and jet) mixing technologies.

6. Translation Of RNA Medicines From Design To Clinic 3/2/2022

   Understand the advantages and challenges of lipid-based delivery systems for successful translation of RNA into clinical development.

7. Stabilization Of RNA-Loaded Lipid Nanoparticles By Lyophilization 8/15/2025

   Discover how lyophilization enhances RNA-based therapeutics by enabling storage at higher temperatures, which simplifies cold-chain logistics while preserving nanoparticle integrity and biological activity.

8. Nanomedicine Modalities Find Path To Clinic Through Analytics 5/16/2025

   Lipid nanoparticles have revolutionized drug delivery, ushering in a new era of nanomedicine. Discover how advanced analytical tools are accelerating next-generation LNP therapeutics.

9. Unpacking The Importance Of Lipid Nanoparticle Production Platforms 4/15/2024

   Batch processing platforms for LNPs lack efficiency, appropriate controls, and yield optimization. Continuous manufacturing platforms may address some of those issues.

10. Developing A Scalable RNA-LNP Drug Product For Clinical Translation 9/22/2022

    Accelerate essential process development activities with instrumentation solution allowing for highly reproducible and scalable production of RNA-LNPs.