RNA Formulation Resources

1. Mixing Technology: Linear Scalability And Mixing Precision For Nanoparticle Formulation 8/5/2025

   Find out how you can achieve precise control and linear scalability in nanoparticle formulation with mixing technology that minimizes batch-to-batch variability and simplifies the scale-up process.

2. The Paradigm Shift: From Scale-Up To Scale-Out In Genetic Medicine 2/18/2025

   The shift from "scale-up" to "scale-out" in genetic medicine enhances production speed, revolutionizing pharmaceutical manufacturing and accelerating life-saving therapies for global patient populations.

3. Ophthalmic Drug Delivery 4/11/2024

   Explore the challenges to effective delivery of drugs to the eye, intricacies of ophthalmic drug delivery, and advantages of nanoparticles as an enabling technology for ocular drug-delivery systems.

4. Developing A Comprehensive Regulatory Approach For LNP Drugs 2/26/2024

   The path to regulatory approval for LNPs demands carefully considered strategies. By adopting proactive and strategic approaches, developers can overcome regulatory hurdles on the path to approval.

5. Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines 3/24/2025

   Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.

6. Tangential Flow Filtration Of LNPs Results In 10X Concentration Within 20 Minutes 8/5/2025

   Dive into a study that details how a single-pass tangential flow filtration system can achieve a tenfold concentration of liposomal nanoparticles in under 20 minutes.

7. The Heroes Of Vaccine Development: Lipid Nanoparticles 2/8/2024

   Lipid nanoparticles (LNPs) have played a crucial role in COVID-19 vaccine development as efficient mRNA delivery systems, exhibiting versatility and effectiveness in accelerating the process.

8. Development And Optimization Of LNP Formulations 12/6/2024

   The production of lipid nanoparticles (LNPs) is a process that demands robustness, scalability, and reproducibility. Examine the impact of key operational parameters on the efficacy of LNPs.

9. An Introduction And Brief History Of mRNA-LNPs 12/14/2023

   With adjustable components and increased stability during bloodstream circulation, LNPs are significantly advancing drug development and delivery, particularly for mRNA vaccines.

10. Enabling Continuous Manufacturing For CAR-T And LNP-Based Therapies 6/27/2025

    Breakthrough therapies are challenged by complex, batch-based manufacturing. A novel, integrated system enables continuous processing, improving consistency and reducing manual handling for advanced modalities.