Stabilization Of RNA-Loaded Lipid Nanoparticles By Lyophilization

Strict, ultra-cold chain processes are necessary to maintain the viability and quality of RNA-based vaccines and therapeutics. Effective management of cold-chain logistics requires precise coordination from start to finish, including temperature monitoring, real-time tracking for traceability, and well-trained and skilled logistics personnel to ensure retention of product quality. Therefore, defining strategies to increase the stability of RNA-based medicines in relatively higher temperatures is essential.

Read this whitepaper to learn how lyophilization of RNA-loaded lipid nanoparticles enables the storage and shipment of therapeutic formulations at logistically convenient temperatures while preserving their physical properties and biological performance.