RNA Formulation Resources

  1. Advancing A LNP Formulation To Clinical And Commercial Manufacturing 3/25/2024

    Lipid selection impacts the final LNP drug product and the LNP process. Review critical quality considerations for lipids and the process requirements for successful commercial-scale manufacturing.

  2. Where Can Novel Non-Viral Polymeric Delivery Agents Take Us? 1/18/2023

    Explore ongoing work to harness different types of HDR templates in order to build cutting-edge systems with the potential to enable point-of-care cell and gene therapy manufacture.

  3. Harnessing Chemistry For Scalable Manufacture Of Lipids Used In mRNA Delivery 1/28/2025

    Discover how scalable lipid nanoparticle (LNP) technology is revolutionizing mRNA-based therapies and shaping the future of treatment innovation.

  4. Cell And Virus Banking In OV Development And Manufacturing 5/14/2024

    Delve into the exciting potential of OVs, including the critical role of cell and virus seed banks, and discover key considerations for establishing cell and virus banks for OV production.

  5. Hemophilia - Global Clinical Trial Landscape 11/7/2023

    Delve into the clinical landscape of hemophilia, a rare X-linked congenital bleeding disorder, across three key regions of the globe, namely Asia Pacific, Europe, and North America.

  6. An Introduction And Brief History Of mRNA-LNPs 12/14/2023

    With adjustable components and increased stability during bloodstream circulation, LNPs are significantly advancing drug development and delivery, particularly for mRNA vaccines.

  7. Building A Chromatography Platform For Purification, Full Capsid Enrichment 7/18/2024

    Developing a robust chromatography platform for AAV8 purification and full capsid enrichment ensures high gene therapy product quality, addressing the challenge of empty capsid removal.

  8. How To Make The Best LNPs 1/22/2024

    There are various factors that require careful consideration throughout the process of formulating LNPs and utilizing them for successful mRNA delivery and translation.

  9. Optimizing Lipid Formulations For Targeted RNA-LNP Applications 9/13/2022

    Learn about the considerations and challenges of using ionizable lipids, including the 5 types of lipids used for RNA delivery.

  10. Freezing mRNA: Best Practice 7/14/2023

    By following some of the best practices in freezing mRNA, you can effectively balance product quality, cost-effectiveness, process safety, and efficiency.