RNA Analytical/Quality Videos

  1. The Latest And Greatest Technological Innovations In mRNA-LNP Production 2/10/2025

    In this segment, Replicate Biosciences’ Andy Geall, Qian Ruan, & Alex Aust identify the most promising technological and raw material innovations that are influencing the drug substance and drug product production processes at CDMOs.

  2. Strategies To De-Risk Next-Gen mRNA Raw Materials 12/3/2025

    In this Advancing RNA Live clip, Khaled Yamout and Sanofi’s Francoise Ribes share the quality considerations that are top of mind when evaluating a novel raw material, as well as how the broader industry (i.e., standard setting organizations, suppliers, and biotechs) can arrive at a clearer understanding of a material’s quality.

  3. Improving IVT Processes: Addressing Analytical Limitations & PAT Shortcomings 4/11/2025

    Advancing RNA Live panelists identify what is “as good as we can get right now” in terms of understanding our IVT reactions while sharing their ideas on how we can arrive at a future that includes real-time monitoring of our drug substance production processes.

  4. Addressing The Challenges Of LNP Upscaling 11/20/2025

    Overcome LNP upscaling challenges by leveraging fluid mechanical principles. Learn how Impingement Jets Mixing achieves reproducible turbulence and consistent LNP quality across all production scales.

  5. Optimizing Oligo Storage For CGT Product Development And Manufacturing 5/9/2023

    Discover how to integrate appropriate materials and tools for oligonucleotide handling, optimize DNA storage using dedicated fluoropolymer film, perform complex biochemical reactions in bags, and more.

  6. Development Of COVID-19 Vaccine Production During A Pandemic 2/20/2025

    See how seamless teamwork and automated electrophoresis systems ensured rapid, reliable COVID-19 vaccine production support and how their collaboration made a difference.

  7. The Evolutions Of mRNA Analytical Development (So Far) 8/22/2024

    Linear mRNA analytical development has been rapidly advancing in the past few years and this panel discussion explores some of the biggest changes we’ve seen in the linear mRNA analytical paradigm.

  8. Assessing The Quality & Maturity Of The Next-Gen Oligo Supply Chain 12/3/2025

    As our molecules grow more complicated, so, too, does the supply chain. Here, Advancing RNA Live speakers Khaled Yamout & Camp4’s Satya Kuchimanchi talk through how this growth challenges our understanding of raw material quality and how sponsors can better assess their suppliers.

  9. Purification Of DNA Oligonucleotides Using AEX Chromatography Webcast 4/25/2023

    Explore impurities removed by strong anion exchange chromatography for the advancement of these molecules as therapeutics and a cost-effective, efficient, and scalable purification method.

  10. Quality Concepts In GMP IVT mRNA Development, Manufacturing, And Analytics 2/13/2025

    Stay ahead in mRNA therapeutic development by mastering the essential quality systems, process controls, and analytical methods required for robust GMP production and efficient manufacturing.