RNA Analytical/Quality Videos

  1. RNA Interference - From Single Gene Studies To Whole Genome Screens 11/7/2022

    Endoribonuclease-prepared siRNAs (esiRNAs) are able to overcome the limitations of RNAi. Learn about esiRNAs, their advantages over standard siRNAs, and ways this technology is utilized in different research fields.

  2. Robust And Cost-Effective mRNA Capping 12/8/2025

    Master the essential strategies for cost-effective and robust mRNA capping at industrial scale. Learn how to successfully evaluate new materials and optimize your synthesis process for maximum efficiency and yield.

  3. Is QbD Actually Possible In mRNA Development Today? 8/22/2024

    As the panelists of this Advancing RNA LIVE discussion argue, there are several big limitations we face in implementing QBD today for RNA development.

  4. Development Of A Mitra Tip Extraction Assay Coupled With LC-MSMS 1/15/2025

    Watch this rundown of a novel method for quantifying L-Citrulline, L-Arginine, and L-Argininosuccinic acid using Mitra tip extraction coupled with LC-MS/MS for enhanced accuracy and reproducibility.

  5. Don't Forget These Important Points When Selecting An RNA CDMO 8/22/2024

    Together, Omega’s Jeff Atkinson & Sail Biomedicines’ Jim Nolan share their perspectives on the health of the linear mRNA and circRNA outsourcing sector.

  6. The Make-or-Break Quality Attributes of Plasmid DNA 10/15/2025

    We all know that plasmid quality is foundational in dictating the quality of the final mRNA drug substance. In this clip homing in on upstream process considerations, speakers Stu Sundseth (Tune Therapeutics), Marc Wolfgang (Sail Biomedicines), and Christian Dohmen (Ethris) outline some of the most important CQAs for plasmids and the impact they can have on the resulting quality of the mRNA drug substance for linear mRNA. 

  7. The Price of Progress: Unlocking Cost Efficiencies in mRNA-LNP Production 4/11/2025

    In this final segment of an Advancing RNA Live discussion, panelists April Sena, Tyler Goodwin, and Adi Nair share the most meaningful and manageable improvements the industry can be making today to upstream and downstream processes to drive down mRNA-LNP COGS.In this final segment of an Advancing RNA Live discussion, panelists April Sena, Tyler Goodwin, and Adi Nair share the most meaningful and manageable improvements the industry can be making today to upstream and downstream processes to drive down mRNA-LNP COGS.

  8. Nanoassemblr Blaze mRNA Vaccine Demo 4/13/2022

    NxGen Technology delivers a scalable means to perform the critical particle formation step in a nanomedicine development process.

  9. Sustainable Vaccine Manufacturing: Securing The Future Of Global Health 7/22/2025

    Explore how next-gen technologies, from mRNA platforms to digital tools, are transforming vaccine manufacturing to make it more sustainable, flexible, and accessible.

  10. Why We Still Haven't Solved mRNA Scale-Up 10/15/2025

    While we can make lots of mRNA at a smaller scale, when it comes to scaling up to kg quantities of mRNA, our current batch processes leave a lot to be desired. Together, Stu Sundseth of Tune Therapeutics and Christian Dohmen of Ethris unpack the biggest barriers to scaling IVT to achieve the desired yield and quality of mRNA, offering their take on how the field is innovating to overcome these issues.