RNA Analytical/Quality Videos

  1. LC/MS/MS Analysis Of Coproporphyrin 1, Coproporphyrin 3 In Human Plasma 2/17/2025

    This innovative approach holds promise for reducing the need for extensive clinical drug-drug interaction studies, potentially streamlining the drug development process.

  2. Don't Forget These Important Points When Selecting An RNA CDMO 8/22/2024

    Together, Omega’s Jeff Atkinson & Sail Biomedicines’ Jim Nolan share their perspectives on the health of the linear mRNA and circRNA outsourcing sector.

  3. The 20-Method Hurdle: Confronting the Operational Burden of mRNA Release 6/9/2026

    Though this Advancing RNA Live panel believes we’re still at too early a stage to begin reducing the number of methods we need for release, Sanofi’s Philippe Talaga, AbbVie’s Elaine Peters, and Tessera’s Ilya Shestopalov had a few ideas on what we can/should be doing today to set us up for more streamlined release panels in the future.  

  4. Customized mRNA Processing For Improved Therapy Development And Manufacturing 2/13/2025

    Optimize mRNA development by learning key strategies for process refinement, critical component identification, and in-process analytics to enhance therapeutic production.

  5. Outgrowing Legacy Methods: mRNA's Transition from Protein Paradigms 6/9/2026

    AbbVie’s Elaine Peters, Sanofi’s Philippe Talaga, and Tessera’s Ilya Shestopalov highlight the technical limitations of legacy analytical methods in evaluating and measuring mRNA-LNP concentration, structure, purity, integrity, and impurities.

  6. Closing the Gap: How NIST is Addressing gRNA Quality 4/29/2026

    Life Edit Therapeutics’ April Sena provides an update on NIST’s gene editing consortium, teasing forthcoming deliverables from a working group focused on gRNA quality. 

  7. The State Of CircRNA Analytical Development 8/22/2024

    Advancing RNA LIVE panelist Jim Nolan of Sail Biomedicines fills us in on the extent to which we can rely on the linear mRNA analytical foundations established today.

  8. Streamline Your mRNA Purification Steps 3/4/2025

    Ensure your mRNA's stability and effectiveness post-transcription with advanced filtration and chromatography techniques to enhance purity and recovery, which delivers high-quality mRNA for superior therapeutics and vaccines.

  9. Circular RNA Process Development: A Quick Primer 10/15/2025

    In this Advancing RNA Live clip, Sail Biomedicines’ Marc Wolfgang gives us a brief primer on the main differences and challenges in developing an IVT reaction for circular RNA, as opposed to linear mRNA.    

  10. Master Your mRNA Manufacturing 3/4/2025

    Join pDNA and mRNA specialists as they discuss innovative mRNA manufacturing solutions for your purification challenges, mRNA stability, and overall product quality.