RNA Analytical/Quality Videos

  1. Analyzing COVID-19 Vaccine Purity Using LC-MS Technologies 11/8/2022

    Explore why process-related impurities are a concern in vaccines and present results and learnings from LC-MS analyses of several mRNA- and protein-based vaccines for COVID-19.

  2. Bioinformatics In mRNA Development: Classification And Integration Conundrums 6/24/2025

    As both Advancing RNA Live speakers point out in this segment, the MHRA guidance focuses deeply on the critical role bioinformatics and AI/ML approaches will play in the development of personalized immunotherapies. Here, Eliquent Life Sciences’ Tiffany Lucas and CureVac’s Ulrike Jägle address the biggest challenges they anticipate companies will face in meeting the agencies’ recommendations.

  3. Why Current dsRNA Analytics Don't Quite Cut It 10/15/2025

    In this Advancing RNA Live segment, several speakers raise concerns about the industry's ability to accurately measure impurities, particularly dsRNA, arguing that current analytics are insufficient, especially for high-dose therapeutics.

  4. The Latest And Greatest Technological Innovations In mRNA-LNP Production 2/10/2025

    In this segment, Replicate Biosciences’ Andy Geall, Qian Ruan, & Alex Aust identify the most promising technological and raw material innovations that are influencing the drug substance and drug product production processes at CDMOs.

  5. Beyond Solid Phase: Weighing Supply Chain Readiness For Liquid Phase & Hybrid Oligo Synthesis 12/3/2025

    The oligo manufacturing paradigm is facing several different evolutions whether it be the transition to liquid-phase or hybrid synthesis. In this Advancing RNA Live clip, Camp4’s Satya Kuchimanchi explores how these manufacturing advancements are impacting our supply chain needs.

  6. LC/MS/MS Analysis Of Coproporphyrin 1, Coproporphyrin 3 In Human Plasma 2/17/2025

    This innovative approach holds promise for reducing the need for extensive clinical drug-drug interaction studies, potentially streamlining the drug development process.

  7. A&M STABTEST Shares QC Analysis Of Oligo Therapeutics 9/20/2022

    Explore best practices for developing a QC method for identification and impurity analysis of oligonucleotides, as well as tips on mitigating risk by using compliant instrumentation and software.

  8. AuroraTX: Ultra-Sensitive, Precise Structural Measurements Of Your Biomolecules 6/12/2025

    Gain key insights into your biomolecules' structure and stability with an advanced, automated measurement technique. Unlock precise, label-free analysis across diverse sample types and conditions.

  9. Don't Forget These Important Points When Selecting An RNA CDMO 8/22/2024

    Together, Omega’s Jeff Atkinson & Sail Biomedicines’ Jim Nolan share their perspectives on the health of the linear mRNA and circRNA outsourcing sector.

  10. 3 Must-Improve Areas in mRNA Process Development 10/15/2025

    In this Advancing RNA Live clip, panelists Stu Sundseth, Marc Wolfgang, and Christian Dohmen each provide their take on the most critical areas for improvement in mRNA process development.