RNA Analytical/Quality Videos

1. How A Sponsored CMC Platform Accelerates mRNA Projects Into The Clinic 1/31/2023

   Developing a client-sponsored Target Product Profile (TPP) and Analytical Target Profile (ATP) is critical to move your drug product to clinic efficiently and meet acceptance criteria.

2. What Does 2025 (And Beyond) Hold For The RNA-LNP Space? 12/4/2024

   Three LNP experts share their thoughts on the incremental advancements they’d like to see the RNA-LNP space make in the next few years.

3. Decoding Regulatory Expectations: The Art Of A Successful IND Submission 6/24/2025

   Companies often underestimate the information required for IND submissions, particularly in a sector that’s as diverse as the mRNA sector. Here, former FDA reviewer Tiffany Lucas shares some of the missteps companies can make when first approaching the FDA with their IND. CureVac’s Ulrike Jägle furthers the discussion, offering a critical best practice she and her colleagues rely upon as well to streamline their regulatory interactions.

4. What The EMA Guidance Means For mRNA: Progress, Limitations, And Future Directions 6/24/2025

   Advancing RNA panelists Tiffany Lucas and Ulrike Jägle home in on the EMA’s guidance for mRNA vaccine quality, sharing their initial thoughts on the guidance’s strengths, while also addressing its limitations for those of us who may be working with mRNA in a therapeutic context.

5. CMC Innovations Worth Watching In The RNA-LNP Space 12/4/2024

   Sanofi’s Sumit Luthra shares several of the analytical and manufacturing innovations/improvements he’s watching and waiting for that will improve our knowledge of LNP composition, structure, function, and quality.

6. Your Roadmap For Efficient Processes 3/4/2025

   Struggling with mRNA integrity? Discover essential strategies to boost stability in mRNA manufacturing with innovative endonuclease-free DTT and Spermidine chemicals.

7. Why Current dsRNA Analytics Don't Quite Cut It 10/15/2025

   In this Advancing RNA Live segment, several speakers raise concerns about the industry's ability to accurately measure impurities, particularly dsRNA, arguing that current analytics are insufficient, especially for high-dose therapeutics.

8. The State Of CircRNA Analytical Development 8/22/2024

   Advancing RNA LIVE panelist Jim Nolan of Sail Biomedicines fills us in on the extent to which we can rely on the linear mRNA analytical foundations established today.

9. Addressing The Challenges Of LNP Upscaling 11/20/2025

   Overcome LNP upscaling challenges by leveraging fluid mechanical principles. Learn how Impingement Jets Mixing achieves reproducible turbulence and consistent LNP quality across all production scales.

10. AuroraTX: Ultra-Sensitive, Precise Structural Measurements Of Your Biomolecules 6/12/2025

    Gain key insights into your biomolecules' structure and stability with an advanced, automated measurement technique. Unlock precise, label-free analysis across diverse sample types and conditions.