RNA Analytical/Quality Videos

1. A Wishlist For The Future: The Next Frontier Of The mRNA & Oligo Supply Chains 12/3/2025

   Here, Advancing RNA Live speakers Khaled Yamout, Sanofi’s Francoise Ribes, and Camp4’s Satya Kuchimanchi share which supply chain advancements they would like to see in the near future, as well as how they anticipate these changes & evolutions could impact each modality’s growth.

2. Improve Bioanalysis Workflows With Integrated Technologies 8/18/2026

   Improve bioanalysis workflows with integrated technologies designed for sensitive biomolecules. Explore how biocompatible systems can support sample integrity, reliable performance, and evolving needs.

3. Bioinformatics In mRNA Development: Classification And Integration Conundrums 6/24/2025

   As both Advancing RNA Live speakers point out in this segment, the MHRA guidance focuses deeply on the critical role bioinformatics and AI/ML approaches will play in the development of personalized immunotherapies. Here, Eliquent Life Sciences’ Tiffany Lucas and CureVac’s Ulrike Jägle address the biggest challenges they anticipate companies will face in meeting the agencies’ recommendations.

4. Fermentation, Analytics, & Quality: Plasmid Production Advancements & Challenges for mRNA Development 4/11/2025

   Advancing RNA Live panelists Tyler Goodwin and April Sena start off our latest discussion on technology innovations in mRNA production by surveying the current manufacturing process for plasmid production, highlighting where they’ve seen advancements and what biotechs need to consider to obtain plasmids of the appropriate quality for mRNA production.

5. Beyond Cas9: How Diverse Nucleases are Redefining gRNA Design 4/29/2026

   As CRISPR technology evolves beyond the original Cas9, gRNAs are transitioning from simple targeting tools into highly engineered, complex molecules. In this Advancing RNA Live segment, speakers April Sena, Max De Long, and Venkat Krishnamurthy discuss how the rise of diverse nucleases — including prime editors — is impacting gRNA synthesis and purity.

6. 3 Must-Improve Areas in mRNA Process Development 10/15/2025

   In this Advancing RNA Live clip, panelists Stu Sundseth, Marc Wolfgang, and Christian Dohmen each provide their take on the most critical areas for improvement in mRNA process development.

7. Primates, Patents, And Progress: Advancements In Rational LNP Design 2/24/2026

   In this opening Advancing RNA Live clip, NanoVation Therapeutics’ Dominik Witzigmann and Stealth Co’s John Zuris share the scientific advancements they’ve been watching most keenly in the LNP space, as well as some of the evolutions they’re seeing in the overall quality of our RNA-LNP products.

8. How "Successful" Are Our mRNA-LNP Outsourcing Partnerships Today? 2/10/2025

   In this snippet, panelist Alex Aust (with the help of several live attendee commenters) tackles a particularly tricky question: Are our outsourcing partnerships producing high quality products today, and what are the most common root causes of batch failures?

9. Optimal Tech For Predicting Drug Responses At The Cellular Level 4/1/2025

   Explore how preserving spatial molecular information and leveraging AI-driven spatial-omics can transform treatment prediction, patient stratification, and personalized medicine.

10. Goldilocks & The Guidances: Finding "Just Right" For RNA Regulations 6/24/2025

    Do we need more specific regulatory guidance for every RNA modality and therapeutic approach? We asked and the Advancing RNA Live audience answered… Here, panelists Tiffany Lucas and Ulrike Jägle address the audience’s responses, as well as share their thoughts on just how prescriptive the future of regulatory guidance for RNA therapeutics approaches could/should be..