Articles, App Notes, Case Studies, & White Papers

  1. IPF - Global Clinical Trial Landscape 5/19/2025

    This report provides a comprehensive overview of Idiopathic Pulmonary Fibrosis (IPF), a progressive and fatal interstitial lung disease.

  2. Low-Volume Production For Screening High-Value Nanoparticle Materials 4/18/2022

    A platform that harnesses microfluidic mixing has been demonstrated as a simple, robust, and scalable production method for LNPs encapsulating various types of nucleic acids.

  3. Modular Bioprocessing Alleviates Drug Manufacturing Woes 4/4/2019

    Building a bioprocessing facility is usually a complicated process and requires partnering with not only drug developers, but also many different experts in various industries.

  4. Quality Control Of Oligonucleotides Using HPLC Coupled To UV And MS Detection 12/6/2024

    Efficient quality control of therapeutic oligonucleotides is crucial. Explore advanced methods combining HPLC-UV and mass spectrometry for precise impurity quantification and mass confirmation.

  5. A Multiplexed High Throughput Method To Evaluate Novel Nuclease Activity 2/24/2025

    Efficiently evaluating the activity of novel nucleases with unique properties requires a high-throughput, multiplexed approach that enables direct comparison across multiple genomic targets.

  6. An Introduction And Brief History Of mRNA-LNPs 12/14/2023

    With adjustable components and increased stability during bloodstream circulation, LNPs are significantly advancing drug development and delivery, particularly for mRNA vaccines.

  7. Genome Editing of Human Primary T Cells With Lipid Nanoparticles 4/18/2022

    We show CRISPR/Cas9-mediated knockouts of the T cell receptor and explore multi-step LNP engineering to produce TCRÉ‘β KO CAR T cells, a promising approach towards allogeneic CAR T cell therapy.

  8. Scaling A mAb Production Process To A Single-Use Platform 9/27/2019

    The transfer of mAb production processes between scales is difficult. In this study, we leveraged existing physical characterization data and scaled a process from microbioreactor to production scale.

  9. Genomic Medicine And The Tools To Realize Its Potential 1/12/2022

    New technologies and collaborations driving the democratization of RNA therapeutics are creating an explosion of opportunity for companies pursuing the development of these transformative medicines.

  10. Nanomedicine Modalities Find Path To Clinic Through Analytics 5/16/2025

    Lipid nanoparticles have revolutionized drug delivery, ushering in a new era of nanomedicine. Discover how advanced analytical tools are accelerating next-generation LNP therapeutics.