Articles, App Notes, Case Studies, & White Papers

  1. Review Of mRNA Vaccines & Therapeutics Manufacturing Challenges: Plasmid DNA Manufacturing 6/7/2022

    This review suggests technical remedial options for the production of pDNA and focuses on mRNA synthesis, purification, and encapsulation.

  2. Lysate Clearance To Remove Cellular Debris 9/13/2021

    The most problematic step in the purification of synthesized biomolecules is the clarification of the sample once the cells are lysed. The lysate often contains biomolecule concentrations millions of times higher than the molecule of interest. Here we present a lysate sample preparation procedure using the AcroPrep™ Advance filter plate for lysate clearance that effectively removes unwanted cellular debris from samples.

  3. How Smaller Biotechs Are Rethinking CRO Relationships Post-Pandemic 3/9/2026

    Smaller biotechs are rethinking CRO partnerships, valuing speed, scientific access, flexibility, and transparent pricing over scale — driven by pandemic lessons and a sharper focus on operational fit.

  4. De-Mystifying, De-Risking Process Development With A CDMO 11/27/2018

    An overview of how CDMOs can help companies get started in the world of CGT manufacturing, with considerations around timing of engagement to maximize commercial and clinical success.

  5. Europe At A Crossroads: Biotech Investment, Regulation, And Partnership In Real Life 12/10/2025

    Position your biotech for Europe’s next phase by aligning strong science, smart clinical strategy, and the right global partners to navigate funding, regulation, and growth.

  6. Capitalize On Regulatory Expertise To Simplify FDA Complexities 5/9/2023

    Get an overview of the global approval landscape, pathways to approval, and the importance of a robust clinical development program as made possible with the help of an experienced CRO.

  7. How Clinical Trials Work 4/4/2025

    Explore a comprehensive overview of clinical trial designs and protocols; including the four distinct phases, eligibility criteria, and essential methodologies.

  8. What Sponsors Get Wrong When Selecting A CRO 3/9/2026

    Gene therapy immunogenicity requires platforms, judgment, and regulatory fluency beyond ADA norms. Relying on biologics criteria creates gaps; CGT expertise ensures reliable, interpretable results.

  9. Location Considerations For Successful Clinical Trials 9/12/2023

    Consider the advantages associated with conducting early- to late-phase clinical trials in China and the broader APAC region, as well as potential challenges that could impact the trial process and patient outcomes

  10. Analytical Method Release And Stability Platform For RNA Drug Substance 3/14/2025

    We offer comprehensive analytical support across the R&D space, including method development, validation, process characterization, in-process testing, process validation, and GMP release testing.