Articles, App Notes, Case Studies, & White Papers

  1. PUPSIT As Part Of A Contamination Control Strategy (CCS) 8/21/2024

    Learn about the changes introduced in the latest revision to EU GMP Annex 1, and gain insight into the components that should be part of a PUPSIT risk assessment.

  2. Getting Genomic Medicines Ready For Prime Time 2/5/2024

    Explore the benefits of building a manufacturing process early, how research into LNPs in nucleic acid therapeutics will contribute to the development of future drugs, and more.

  3. Suitability Testing For IVT mRNA Analysis 11/20/2025

    Automated capillary electrophoresis provides robust, precise analysis of IVT mRNA integrity, concentration, and size, demonstrating excellent method precision.

  4. When Should Filter Validation Be Performed? 8/21/2024

    Learn about a program that has been developed to facilitate risk mitigation before process-specific filter validation is performed.

  5. Elevating mRNA Manufacturing Toward GMP-Readiness 8/27/2025

    The mRNA Technology Transfer Program empowers LMICs with scalable vaccine production. Learn about a partnership that drives innovation in mRNA and sets a global blueprint for equitable health access.

  6. Automated Cell Bleed Control In An Intensified SU Rocking Motion Bioreactor 11/20/2019

    Intensified processing increases the productivity of single-use facilities and decreases the manufacturing footprint. Here's how to optimize the approach.

  7. dsRNA: Why Polymerase Choice Matters 3/17/2026

    Polymerase selection during IVT shapes dsRNA levels, processing costs, and product quality. See how enzyme engineering reduces abortive transcripts and improves purity profiles for complex mRNA manufacturing applications.

  8. Extending The Lower Limits Of Quantification Of A Therapeutic Oligonucleotide Through Microflow LC-MS/MS 3/4/2022

    Here a solution is presented to widely recognized challenges with ionpairing reversed phase liquid chromatography (IP-RP LC) through a novel microflow LC-MS strategy.

  9. Understanding And Controlling Raw Material Variation In Cell Culture Media 9/5/2019

    An organized effort across biopharma, including drug substance manufacturers and suppliers, is needed to address and meet the needs of industry regarding raw material quality and consistency.

  10. Quality Assurance In IVT RNA Vaccine Development Using Electrophoresis 2/20/2025

    Discover advanced solutions for IVT RNA synthesis, focusing on enhancing fidelity in throughput, innovative technologies, and methodologies to optimize your RNA research and development processes.