Articles, App Notes, Case Studies, & White Papers

1. The Future Is Now: CGT Innovation, Challenges, And Perspectives 7/19/2023

   As CGTs advance toward clinical trials, developers face a number of challenges such as navigating a shifting regulatory landscape and employing beneficial manufacturing processes.

2. An Exploration Of ICIs In Cancer Therapy 1/31/2024

   This collection of frequently asked questions highlights the remarkable efficacy of immune checkpoint inhibitors (ICIs) and the projected growth of the global ICI market.

3. A Risk-Based Approach To Validation Studies For Sterilizing-Grade Filtration And Single-Use Systems 10/3/2024

   One way to address risk related to product quality is by implementing a Question-Based Review approach. Read on to learn about this approach and its advantages.

4. Benefits Of PCR-Based mRNA Manufacturing Processes 5/17/2024

   Learn about a proprietary polymerase chain reaction (PCR) solution that was developed to overcome the challenges associated with pDNA that applies the high accuracy of PCR to mRNA manufacturing.

5. Review Of mRNA Vaccines & Therapeutics Manufacturing Challenges 10/11/2022

   Learn more about the challenges that arise during the synthesis, purification, and encapsulation of mRNA.

6. Targeted LC-MS/MS Detection Of Lipid Impurities In Lipid Nanoparticles 12/9/2024

   Learn about an HPLC-MS/MS method for detecting lipid impurities in lipid nanoparticles (LNPs) and why it is critical for quality control of LNP-based drug delivery systems.

7. 24-Well Filter Plates Offer Alternative For Clarifying Mammalian Cell Cultures 12/11/2020

   Centrifugation and filtration have been widely accepted as techniques required for clarifying complex cell cultures to recover extracellular proteins such as monoclonal antibodies (mABs). Read an alternative to the use of centrifugation/filtration/flocculation to clarify mammalian cells cultures and describes assessment of newly developed AcroPrep 24-well clarification and sterilization plate and AcroPrep 24-well sterilization plate for clarification of mammalian cell cultures (2 to 26 x 10⁶ cells/mL) and recovery of proteins present in the supernatant.

8. The Business Case For Sustainability ― From Industry Resilience To Bottom Line Impact 9/3/2024

   Explore key insights into how sustainability efforts are influencing business outcomes from a survey that collected data from 800 pharma and biopharma executives across 18 countries.

9. Pioneering The Future Of Pharmaceutical Supply Chains

   Drive the efficiency and resiliency of supply chains by integrating automation, AI, and effective communication, ensuring the successful distribution of lifesaving medicinal products.

10. The Execution Stage Of Technology Transfer 5/2/2024

    What are the key elements in the readiness stage of a technology transfer that are critical to your success? Explore Process Performance Qualification (PPQ) and the execution stage of PDA TR-65.