Articles, App Notes, Case Studies, & White Papers

1. Regulatory Compliance In Clinical Research 3/28/2025

   Understand the critical aspects of regulatory compliance, and gain insights into how you can safeguard participant rights and ensuring the integrity of clinical research.

2. Review Of mRNA Vaccines & Therapeutics Manufacturing Challenges: Plasmid DNA Manufacturing 6/7/2022

   This review suggests technical remedial options for the production of pDNA and focuses on mRNA synthesis, purification, and encapsulation.

3. Potent Immune Response With Vernal's LNP-mRNAs 4/26/2024

   As mRNA medicine continues to evolve, understand how trusted manufacturing partners will continue to play a pivotal role in translating innovative concepts into clinical reality.

4. Accelerating Cold Chain Expansion: Responding To COVID-19 Challenges 8/21/2024

   Review how leveraging cross-functional teamwork helped complete a cold chain infrastructure expansion in a fraction of the expected timeline, ensuring the production of essential COVID-19 therapeutics.

5. CRISPR Off-Target Editing: Prediction, Analysis, And More 2/28/2025

   A crucial consideration for researchers is off-target editing – unintended DNA modifications at sites other than the intended target. Explore the complexities and strategies to mitigate these effects.

6. Developing A Comprehensive Regulatory Approach For LNP Drugs 2/26/2024

   The path to regulatory approval for LNPs demands carefully considered strategies. By adopting proactive and strategic approaches, developers can overcome regulatory hurdles on the path to approval.

7. The Future Of Clinical Trials: Embracing Virtualization, RQE, And AI 9/12/2023

   Delve into the swiftly evolving trends that are reshaping the clinical trial industry and examine potential implications for introducing innovative solutions to the market.

8. Molecular Weight Confirmation For Length, Integrity And Impurity Analysis Of A 70-Mer Oligonucleotide 9/8/2023

   Explore a workflow used to determine the molecular weight and analyze the purity of a 70-mer DNA sequence with a 3’ dT overhang.

9. Residual Plasmid Quantification In Gene Therapy Manufacturing Workflows 6/7/2024

   This article details the design and application of a Plasmid DNA - Kanamycin Resistance Gene (pDNA-KanR) kit for residual plasmid quantification in gene therapy manufacturing.

10. mRNA Product Purification Process Strategies 2/15/2023

    Impurities from IVT can induce undesired immune responses and negatively impact translation efficiency. Explore the pros and cons of each option for mRNA purification.