RNA Supply Chain Videos

1. The State of the Linear mRNA Supply Chain—In Brief

   In this clip, Sanofi’s Greg Troiano kickstarts our discussion on some of the advances he’s seen in the supply chain for linear mRNA-LNP products, both in terms of supply availability and supplier capability.

2. Next Generation GMP Facility For CRISPR Based Therapies 3/14/2023

   Explore a state-of-the-art GMP facility focused on CRISPR based Cell and Gene therapies with helping temperature controlled warehouse and multiple synthesis suites.

3. End-To-End Cold Chain Management: A Next-Generation Approach 2/26/2024

   Three experts in cold chain management walk through the advantages of end-to-end platforms for bulk drug substance management.

4. The Way Forward: Supply Chain Solutions 10/24/2024

   Learn how to build a resilient supply chain to navigate today's complex environment. Expert speakers share insights on optimization, innovation, and strategic planning to meet evolving market conditions.

5. Addressing Industry Challenges In mRNA Product Commercialization

   While the speed of production and flexibility of mRNA are appealing, several industry challenges must still be addressed to realize the full potential and further expand its use.

6. How Are The Costs Of mRNA-LNP Manufacturing Evolving? 2/10/2025

   Achieving cost-effective manufacturing while maintaining high quality standards today is one of the biggest challenges facing companies outsourcing mRNA/RNA development. In turn, panelists Qian Ruan, Andy Geall, and Alex Aust reflect on how and where they’ve seen the costs of mRNA-LNP manufacturing evolving/fluctuating in recent years.

7. Don't Ignore These Functional Areas In Your RNA Therapeutic's Regulatory Story 5/10/2024

   Explore two functional areas that Advancing RNA panelists consider most essential to telling an RNA product’s “story” thoroughly to regulators.

8. Fermentation, Analytics, & Quality: Plasmid Production Advancements & Challenges for mRNA Development 4/11/2025

   Advancing RNA Live panelists Tyler Goodwin and April Sena start off our latest discussion on technology innovations in mRNA production by surveying the current manufacturing process for plasmid production, highlighting where they’ve seen advancements and what biotechs need to consider to obtain plasmids of the appropriate quality for mRNA production.

9. How Could saRNA & circRNA Simplify Manufacturing & Supply Chain Management?

   Explore the broad benefits and challenges that could be encounter by working with self-amplifying and circular RNA modalities — particularly in terms of manufacturing, raw material supply, COGS, and patient centricity.

10. Is The IVT Reaction A Coy Mistress? The Knowns & Unknowns 4/24/2023

    In this Bioprocess Online Live panel, we discuss two experts' perspectives on the current state of the mRNA supply chain for critical raw materials and manufacturing supplies and where pain points still exist.