RNA Supply Chain Videos

1. What's Next In IVT Technology? Innovations in Focus 4/11/2025

   Advancing RNA Live panelists delve into advancements in IVT technology, homing in on innovations like bead-based purification, improved enzymes, and modular manufacturing systems.

2. Is The IVT Reaction A Coy Mistress? The Knowns & Unknowns 4/24/2023

   In this Bioprocess Online Live panel, we discuss two experts' perspectives on the current state of the mRNA supply chain for critical raw materials and manufacturing supplies and where pain points still exist.

3. Synthetic pDNA: Is It Ready For mRNA Production Primetime? 4/11/2025

   Together, this Advancing RNA panel briefly addresses the ongoing rise of synthetic pDNA, sharing the current benefits and limitations of working with this technology for plasmid production today.

4. End-To-End Cold Chain Management: A Next-Generation Approach 2/26/2024

   Three experts in cold chain management walk through the advantages of end-to-end platforms for bulk drug substance management.

5. Analytical Limitations In Assessing Plasmid Quality for mRNA Production 4/11/2025

   There remain a lot of gaps in our understanding of plasmid quality, particularly for high-quality mRNA production (as opposed to viral vector production). In this segment of a recent Advancing RNA Live panel, speakers Adi Nair, Tyler Goodwin, and April Sena highlight their biggest questions around plasmid DNA quality, as well as the pros and cons of some of the analytical methods upon which we’re relying most heavily today to assess plasmid quality.

6. Empowering Your Plasmid DNA Workflow 3/4/2025

   Unlock the full potential of your pDNA purification with advanced chromatography solutions and resins that tackle high viscosity and impurities to ensure superior quality and yield.

7. Don't Ignore These Functional Areas In Your RNA Therapeutic's Regulatory Story 5/10/2024

   Explore two functional areas that Advancing RNA panelists consider most essential to telling an RNA product’s “story” thoroughly to regulators.

8. Single-Use Technology For Quality mRNA Manufacturing

   Learn how single-use technologies deliver important benefits for mRNA manufacturing, including increased speed, quality, flexibility, and adaptability to different dosages and scale-up strategies.

9. CMC Innovations Worth Watching In The RNA-LNP Space 12/4/2024

   Sanofi’s Sumit Luthra shares several of the analytical and manufacturing innovations/improvements he’s watching and waiting for that will improve our knowledge of LNP composition, structure, function, and quality.

10. The Way Forward: Supply Chain Solutions 10/24/2024

    Learn how to build a resilient supply chain to navigate today's complex environment. Expert speakers share insights on optimization, innovation, and strategic planning to meet evolving market conditions.