RNA Supply Chain Videos

1. Manufacturing Made More Robust And Customer-Centric 12/11/2025

   Discover how regional manufacturing, risk-aware practices, and agile strategies are reshaping supply chains to deliver resilience, transparency, and sustainability in today’s complex global environment.

2. The Purification Dilemma: Balancing Upstream & Downstream Investment 10/15/2025

   This Advancing RNA Live clip dives into the biggest challenges in mRNA purification and the critical debate on where to focus investment. Here, our three mRNA PD experts argue for a holistic process development strategy, challenging the traditional wisdom of optimizing the upstream process at any cost.

3. Defining Phase-Appropriate GMP Principles: Where Do We Start?

   In this excerpt from Advancing RNA Live's Got Raw Materials? The State Of The mRNA Supply Chain featured guests share how they and their teams align around the definition of “phase-appropriate.”

4. Don't Ignore These Functional Areas In Your RNA Therapeutic's Regulatory Story 5/10/2024

   Explore two functional areas that Advancing RNA panelists consider most essential to telling an RNA product’s “story” thoroughly to regulators.

5. The State of the Linear mRNA Supply Chain—In Brief

   In this clip, Sanofi’s Greg Troiano kickstarts our discussion on some of the advances he’s seen in the supply chain for linear mRNA-LNP products, both in terms of supply availability and supplier capability.

6. Why Our Conversations About Supply Chain Should NOT Overlook This Key Aspect

   When asked which specific topic they’d like to see discussed more regularly in the future as it relates to our supply chains, Featured speakers for the "Got Raw Materials? The State Of The mRNA Supply Chain" event were aligned around this one absolutely critical topic...

7. Next-Generation RNA Modality Supply Considerations

   Together, Life Edit Therapeutics’ April Sena and Sanofi’s Troiano share their perspectives on raw material quality & IP-related considerations for managing the supply chain for next-generation RNA modalities.

8. How Are The Costs Of mRNA-LNP Manufacturing Evolving? 2/10/2025

   Achieving cost-effective manufacturing while maintaining high quality standards today is one of the biggest challenges facing companies outsourcing mRNA/RNA development. In turn, panelists Qian Ruan, Andy Geall, and Alex Aust reflect on how and where they’ve seen the costs of mRNA-LNP manufacturing evolving/fluctuating in recent years.

9. The Way Forward: Supply Chain Solutions 10/24/2024

   Learn how to build a resilient supply chain to navigate today's complex environment. Expert speakers share insights on optimization, innovation, and strategic planning to meet evolving market conditions.

10. Can A Small Plasmid Produce Huge Benefits? The Power Of Small 1/17/2023

    With benefits across applications, nanoplasmids are designed to replace antiquated bacterial backbones, while eliminating antibiotic markers that can cause regulatory concerns.