RNA Supply Chain Videos

1. mRNA Supply Chain And Critical Component Risks 10/16/2023

   What challenges do you consider the most formidable in your own mRNA therapeutic development environments?

2. Can A Small Plasmid Produce Huge Benefits? The Power Of Small 1/17/2023

   With benefits across applications, nanoplasmids are designed to replace antiquated bacterial backbones, while eliminating antibiotic markers that can cause regulatory concerns.

3. mRNA Raw Materials To Scale Up Your Manufacturing 11/22/2022

   Learn more about CustomBiotech and what they can provide to meet your mRNA needs.

4. Don’t Ignore These Functional Areas In Your RNA Therapeutic’s Regulatory Story 5/10/2024

   Explore two functional areas that Advancing RNA panelists consider most essential to telling an RNA product’s “story” thoroughly to regulators.

5. Violin Making Meets mRNA | ARW On RNA Ep03 4/5/2023

   Hosted by Cell & Gene Collaborative's Director Anna Rose Welch, ARW on RNA puts a creative spin on the emerging mRNA + RNA therapeutics industry. Here, in Episode 3, Welch explores the similarities that exist between the art of crafting a high quality violin and the upstream process development work mRNA therapeutics experts are performing today to create the most ideal mRNA drug substance.

6. Effective, Efficient Downstream Purification For Plasmid DNA 4/26/2022

   Learn about a complete purification process flow that overcomes the challenges of producing pDNA – a critical first step in mRNA manufacturing – and covers all downstream unit operations.

7. Vector System For Genetic Delivery Optimization 1/17/2023

   Looking to enhance performance and manufacturing from your DNA backbone without the regulatory concerns? Gain advantages over legacy plasmid DNA backbones and minicircles.

8. Discovery To Clinic: CRISPR-Based Therapies And Diagnostics 11/29/2023

   As CRISPR use continues to grow, so has the demand for clinical-grade guide RNA. Learn about GMP sgRNA and their stringent process and manufacturing controls.

9. Evaluation Criteria Of Freezer Systems For Bulk Pharmaceuticals 11/1/2023

   Review data and evidence that demonstrates the benefits of an integrated approach to achieving critical end-user goals such as scalability, efficiency, sustainability, and optimized process economics.

10. The 3 C’s Of mRNA-LNP Material Sourcing

    In response to an audience poll question gauging which cGMP materials have proven the most difficult to source, our speakers provide additional clarity around which IVT & LNP-related materials today are more “commoditized”.