RNA Supply Chain Solutions

  1. in vivo mRNA Delivery Using Liposome-Based Reagent 12/12/2022

    in vivo-jetRNA®+ is a ready-to-use reagent that does not require formulation equipment that leads to 100% mRNA encapsulation leading to efficient mRNA delivery.

  2. Plasmid DNA Production 6/23/2022

    Integrated manufacturing supporting cell and gene therapies.

    The critical genetic foundation for advanced therapies

    Plasmid DNA is a critical raw material for advanced therapies and mRNA synthesis, supporting their transfection to enable rapid advancement of the therapeutic product. Center for Breakthrough Medicines (CBM) offers capacity dedicated to the development and manufacture of high quality plasmid DNA and other nucleic acids.

  3. Plasmid DNA Manufacturing 1/31/2023

    As a critical starting material in the production of many advanced therapies including viral vectors and RNA vaccines, cell and gene therapy research at any scale requires plasmid DNA manufacturing. Our specialists provide custom plasmid production that fits your project specifications. To save time and accelerate your cell and gene therapy programs, we also offer off-the-shelf, premanufactured, High Quality viral vector packaging plasmids.

  4. Vaccinia Capping System mRNA Guanylyltransferase And mRNA Methyltransferase 12/5/2025

    mRNA Vaccinia Capping System: Proven. Scalable. Tailored to the needs of biopharma companies developing mRNA-based therapies.

  5. Prima Product Line Up 3/17/2026

    Discover how specialized RNA polymerase variants solve yield, purity, and capping challenges across different template lengths, with substantive improvements over standard T7 polymerase performance.

  6. GMP sgRNA Manufacturing 11/30/2023

    Transition from early-phase research through process development into the clinic with these continuum sgRNA available in different grades.

  7. INDe sgRNAs For Preclinical Safety, Toxicity, And Efficacy Studies 11/29/2023

    Seamlessly transition from discovery to delivery with INDe sgRNAs. These quality sgRNAs can be synthesized in quantities from milligrams to grams and follow high purity specifications.

  8. Fit-For-Purpose And GMP Grade mRNA Reagents 3/24/2025

    Ensure the safety and efficacy of your mRNA therapeutics with high-quality, GMP-grade reagents from a trusted partner with a multi-tiered quality approach to deliver manufacturing certainty.

  9. Excellence For Cell And Gene Therapy Manufacturing 6/4/2025

    Unlock the potential of advanced therapies with dedicated partnership and tailored manufacturing solutions, ensuring quality and efficiency from discovery through to delivery for next-generation treatments.

  10. Vaccinia Capping System For mRNA Therapeutics 12/5/2025

    Backed by over a decade of expertise in capping enzyme production, this system is a robust, scalable solution designed to support production journeys from early R&D to full-scale manufacturing.