RNA Supply Chain Solutions

  1. in vivo-jetRNA®+ 9/14/2022

    Efficient: 100% mRNA encapsulation leading to comparable LNP delivery results
    in vivo-jetRNA®+ is the reagent of choice to deliver mRNA to various organs. This is attributable to its intrinsic properties: in vivo-jetRNA®+ protects its payload against ubiquitous endonucleases, prevent non-specific interactions with proteins and promote efficient cell entry.

  2. jetMESSENGER®: mRNA Transfection Reagent 3/21/2023

    Take your gene expression to the next level by switching to mRNA!

    Primary cells, neurons, suspension cells and various cancer cell lines are especially challenging to transfect. jetMESSENGER® gives high transfection efficiency in all of these usually difficult to transfect cells, by allowing highly efficient mRNA transfection.

    mRNA transfection is as easy as DNA transfection, with the advantage that mRNA does not need to reach the cell nucleus for expression nor require cell division for efficient gene expression. Hence, cells that are slow dividing or that have developed specific mechanisms to protect their genome can finally be used for gene expression.

    Unravel the full potential of your cells by switching to mRNA transfection.

  3. New Next-Generation GMP Facility 5/16/2023

    A new state-of-the-art GMP facility has been created to accelerate the development of CRISPR-based cell and gene therapies, overcoming challenges such as procuring reliable GMP-grade sgRNA persist.

  4. Vaccinia Capping System For mRNA Therapeutics 12/5/2025

    Backed by over a decade of expertise in capping enzyme production, this system is a robust, scalable solution designed to support production journeys from early R&D to full-scale manufacturing.

  5. Product Launch: Vaccinia Capping System mRNA Guanylyltransferase And mRNA Methyltransferase 12/5/2025

    mRNA Vaccinia Capping System: Proven. Scalable. Tailored to the needs of biopharma companies developing mRNA-based therapies.

  6. Fit-For-Purpose And GMP Grade mRNA Reagents 3/24/2025

    Ensure the safety and efficacy of your mRNA therapeutics with high-quality, GMP-grade reagents from a trusted partner with a multi-tiered quality approach to deliver manufacturing certainty.

  7. Plasmid DNA Production 6/23/2022

    Integrated manufacturing supporting cell and gene therapies.

    The critical genetic foundation for advanced therapies

    Plasmid DNA is a critical raw material for advanced therapies and mRNA synthesis, supporting their transfection to enable rapid advancement of the therapeutic product. Center for Breakthrough Medicines (CBM) offers capacity dedicated to the development and manufacture of high quality plasmid DNA and other nucleic acids.

  8. in vivo mRNA Delivery Using Liposome-Based Reagent 12/12/2022

    in vivo-jetRNA®+ is a ready-to-use reagent that does not require formulation equipment that leads to 100% mRNA encapsulation leading to efficient mRNA delivery.

  9. Excellence For Cell And Gene Therapy Manufacturing 6/4/2025

    Unlock the potential of advanced therapies with dedicated partnership and tailored manufacturing solutions, ensuring quality and efficiency from discovery through to delivery for next-generation treatments.

  10. Mitigate Contamination Risks With HTST Flash Pasteurization 5/2/2024

    Gibco™ High-temperature, short-time (HTST) treatment of raw materials

    HTST treatment currently available in North America

    Simple sugar batch sizes ranging from 800 to 8,800 L

    In-house HTST preparation can be expensive and cumbersome. Outsourcing this technology to Thermo Fisher Scientific can alleviate production bottlenecks and increase viral mitigation confidence.

    Suitable and cost-effective for large volumes

    Standard and custom bioprocessing containers available (5 L–1,000 L). Please contact your sales representative.