RNA Supply Chain Solutions

  1. Plasmid DNA Manufacturing 1/31/2023

    As a critical starting material in the production of many advanced therapies including viral vectors and RNA vaccines, cell and gene therapy research at any scale requires plasmid DNA manufacturing. Our specialists provide custom plasmid production that fits your project specifications. To save time and accelerate your cell and gene therapy programs, we also offer off-the-shelf, premanufactured, High Quality viral vector packaging plasmids.

  2. New Next-Generation GMP Facility 5/16/2023

    A new state-of-the-art GMP facility has been created to accelerate the development of CRISPR-based cell and gene therapies, overcoming challenges such as procuring reliable GMP-grade sgRNA persist.

  3. Excellence For Cell And Gene Therapy Manufacturing 6/4/2025

    Unlock the potential of advanced therapies with dedicated partnership and tailored manufacturing solutions, ensuring quality and efficiency from discovery through to delivery for next-generation treatments.

  4. Mitigate Contamination Risks With HTST Flash Pasteurization 5/2/2024

    Gibco™ High-temperature, short-time (HTST) treatment of raw materials

    HTST treatment currently available in North America

    Simple sugar batch sizes ranging from 800 to 8,800 L

    In-house HTST preparation can be expensive and cumbersome. Outsourcing this technology to Thermo Fisher Scientific can alleviate production bottlenecks and increase viral mitigation confidence.

    Suitable and cost-effective for large volumes

    Standard and custom bioprocessing containers available (5 L–1,000 L). Please contact your sales representative.

  5. Fit-For-Purpose And GMP Grade mRNA Reagents 3/24/2025

    Ensure the safety and efficacy of your mRNA therapeutics with high-quality, GMP-grade reagents from a trusted partner with a multi-tiered quality approach to deliver manufacturing certainty.

  6. Plasmid DNA Production 6/23/2022

    Integrated manufacturing supporting cell and gene therapies.

    The critical genetic foundation for advanced therapies

    Plasmid DNA is a critical raw material for advanced therapies and mRNA synthesis, supporting their transfection to enable rapid advancement of the therapeutic product. Center for Breakthrough Medicines (CBM) offers capacity dedicated to the development and manufacture of high quality plasmid DNA and other nucleic acids.

  7. Advancing Innovative Plasmid DNA Manufacturing Solutions For CGT 3/13/2025

    Having produced over 185,000 DNA lots, including 5,000+ cGMP batches, we are a trusted partner in plasmid DNA production from discovery to commercialization.

  8. Synthetic Research Grade sgRNA Manufacturing For CRISPR Experiments 11/28/2023

    Consistently achieve high editing efficiency and quick turnaround time in as little as 7 days with synthetic sgRNA that pave your way to a successful CRISPR experiment.

  9. High-Fidelity Nuclease For Therapeutic Breakthroughs 10/28/2024

    The hfCas12Max nuclease offers superior gene editing with high fidelity, broad PAM recognition, minimal off-target effects, and compatibility across cell types for therapeutic applications.

  10. GenVoy-ILM™ T Cell Kit For mRNA, Ignite™ 7/1/2022

    GenVoy-ILM™ T Cell Kit for mRNA, Ignite is an lipid nanoparticle (LNP) reagent mix optimized for the delivery of messenger RNA (mRNA) or Cas9 mRNA/sgRNA into activated human primary T cells.