RNA Supply Chain Solutions

1. Process Chemicals For RNA Drug Manufacturing

   Make use of our portfolio of raw materials required for mRNA with an integrated offering for all process steps, from plasmid DNA (pDNA) to mRNA synthesis to final formulation.

2. High-Fidelity Nuclease For Therapeutic Breakthroughs 10/28/2024

   The hfCas12Max nuclease offers superior gene editing with high fidelity, broad PAM recognition, minimal off-target effects, and compatibility across cell types for therapeutic applications.

3. Advancing Innovative Plasmid DNA Manufacturing Solutions For CGT 3/13/2025

   Having produced over 185,000 DNA lots, including 5,000+ cGMP batches, we are a trusted partner in plasmid DNA production from discovery to commercialization.

4. Synthetic Research Grade sgRNA Manufacturing For CRISPR Experiments 11/28/2023

   Consistently achieve high editing efficiency and quick turnaround time in as little as 7 days with synthetic sgRNA that pave your way to a successful CRISPR experiment.

5. T Cell Kit For mRNA On NanoAssemblr Spark 4/14/2022

   The GenVoy-ILM T Cell Kit for mRNA is optimized for the delivery of mRNA into activated primary human T cells using mRNA-LNPs formulated on the NanoAssemblr Spark instrument and cartridges.

6. Brochure: The Power Of Small: Nanoplasmid™ Vector Platform 1/19/2023

   With gene therapy advancing at a record pace, Aldevron recognizes the enormous promise your work can bring to therapeutics. We are proud to deliver a superior, modern plasmid technology to your therapeutic endeavors.

7. jetMESSENGER®: mRNA Transfection Reagent 3/21/2023

   Take your gene expression to the next level by switching to mRNA!

   Primary cells, neurons, suspension cells and various cancer cell lines are especially challenging to transfect. jetMESSENGER® gives high transfection efficiency in all of these usually difficult to transfect cells, by allowing highly efficient mRNA transfection.

   mRNA transfection is as easy as DNA transfection, with the advantage that mRNA does not need to reach the cell nucleus for expression nor require cell division for efficient gene expression. Hence, cells that are slow dividing or that have developed specific mechanisms to protect their genome can finally be used for gene expression.

   Unravel the full potential of your cells by switching to mRNA transfection.

8. Excellence For Cell And Gene Therapy Manufacturing 6/4/2025

   Unlock the potential of advanced therapies with dedicated partnership and tailored manufacturing solutions, ensuring quality and efficiency from discovery through to delivery for next-generation treatments.

9. jetMESSENGER®: mRNA Transfection Reagent For Hard-To-Transfect Cells 3/21/2023

   Learn about a highly efficient and gentle mRNA transfection reagent designed for outstanding transfection efficiency in hard-to-transfect cells, finally allowing relevant gene expression experiments in almost all cell types.

10. New Next-Generation GMP Facility 5/16/2023

    A new state-of-the-art GMP facility has been created to accelerate the development of CRISPR-based cell and gene therapies, overcoming challenges such as procuring reliable GMP-grade sgRNA persist.