RNA Supply Chain Resources

  1. The Role Of CRISPR Cas9 Plasmids In Gene-Editing 12/12/2023

    Plasmids are crucial for CRISPR-Cas9 gene-editing technology, and their role in CRISPR is expected to evolve with ongoing research.

  2. CRISPR sgRNA For Successful Gene Editing: Discovery To Clinic 9/25/2023

    The single guide RNA (sgRNA) is one of the key components of successful CRISPR gene editing. Here we cover all the important aspects of sgRNA and Synthego’s sgRNA products.

  3. Uninterrupted Supply To Meet Demand 1/23/2024

    Explore a solution for biopharmaceutical companies concerned about the risks an increase in campaign volume can pose to their production timeline.

  4. Revolutionizing Patient-Centric Supply Chains To Improve Vaccine Access 3/1/2023

    Transparent collaboration and innovation are essential to establishing an infrastructure that supports more agile business models and empowers widespread vaccine access.

  5. Consolidating The Supply Chain For mRNA 2/12/2024

    Learn about the first end-to-end cGMP facility that was developed for mRNA manufacturing to address the shortage of CDMOs and the inadequate and inefficient supply chain options for sourcing GMP mRNA.

  6. Novel Lipid Nanoparticle Delivery Reagent And Manufacturing Workflow 4/18/2022

    We aim to highlight that commercially available LNP reagent mix, GenVoy-ILM, is an accessible and easy-to-use LNP formulation that allows for rapid preclinical development of RNA vaccines.

  7. GMP-Source® And Phase-Appropriate Use For Early-Stage Clinical Trials 9/16/2021

    GMP-Source is a more robust, less rigid alternative to full cGMP production that mirrors nearly all of the oversight and quality standards of full cGMP production while relaxing certain commercial standards, helping companies overcome the hurdles that can stall early development.

  8. Transitioning From Using RUO To cGMP Chemicals For Clinical Trials 10/17/2023

    Learn about the common challenges and risks associated with accelerating your molecule's timeline from lab to clinic, along with important supply chain considerations for emerging biopharma companies.

  9. Eliminating Antibiotic Resistance Gene Transfer Risks In CGTs 8/14/2023

    Learn about the drawbacks of antibiotic resistance that can cause side effects in patients and how an antibiotic-free approach can ease the burden of regulatory compliance and accelerate development.

  10. Advancing mRNA Therapeutics With High Performance RNA Polymerases 2/9/2026

    Learn how optimized RNA polymerases enhance mRNA therapeutic quality and transcript integrity by increasing yield and capping efficiency while reducing double-stranded RNA impurities.