RNA Supply Chain Resources

1. Reduce Contamination Risks When Storing Synthetic DNA 10/30/2023

   An alternative to traditional polyethylene bags is offering cell and gene therapy manufacturers a solution to contamination concerns regarding DNA or RNA fragments.

2. Demystifying CRISPR gRNA Chemical Modifications 10/28/2024

   Chemical modifications on CRISPR gRNAs enhance stability, editing efficiency, and reduce immune responses, enabling in vivo applications and clinical success.

3. mRNA Vaccine Development: Planning, Workflow, Supply Chain Success 5/17/2022

   A review of insights derived from the development of mRNA-based COVID-19 vaccines and how they can be applied to accelerate progress in the manufacture of vaccines and therapeutics moving forward.

4. Leveraging Single-Use Technology For mRNA-LNP Drug Manufacturing 6/12/2023

   Single-use technology is vital for ensuring the quality and expedited market entry of genomic medicines. Learn how LNP technology is paving the way for a new era of personalized, precise medicine.

5. Optimization Of Transient Transfection Of MSCs With Plasmid DNA Or mRNA 11/1/2022

   Read through the results of our efforts to produce an optimal protocol for the transient transfection of hMSCs with pDNA or mRNA using non-viral means.

6. CRISPR sgRNA For Successful Gene Editing: Discovery To Clinic 9/25/2023

   The single guide RNA (sgRNA) is one of the key components of successful CRISPR gene editing. Here we cover all the important aspects of sgRNA and Synthego’s sgRNA products.

7. Understanding CRISPR Clinical Trials: Your Questions Answered 3/15/2023

   CRISPR technology is revolutionizing cell and gene therapies, but how do CRISPR clinical trials work? Follow this explanation of CRISPR therapies from the discovery phase to FDA approval.

8. Overcome Vaccine Development Complexities With The Right Supply Chain Partner 7/5/2022

   Explore the challenges impacting clinical supply chains and solutions to overcome these complexities, and understand why it is crucial to pick the right supply chain provider for vaccine storage and distribution.

9. Revolutionizing Patient-Centric Supply Chains To Improve Vaccine Access 3/1/2023

   Transparent collaboration and innovation are essential to establishing an infrastructure that supports more agile business models and empowers widespread vaccine access.

10. Enabling CDMOs To Focus On Core Priorities 4/26/2024

    Explore innovative solutions for CDMO's striving to remain competitive as the biopharmaceutical market grows and evolves.