RNA Supply Chain Resources

1. Understanding The Hidden Value Of Quality 6/26/2023

   Costs of poor quality (COPQ) cannot be overstated. Review the statistics that prove how costly it can be to avoid resolving quality issues in your processes and supply chain.

2. mRNA Vaccine Development: Planning, Workflow, Supply Chain Success 5/17/2022

   A review of insights derived from the development of mRNA-based COVID-19 vaccines and how they can be applied to accelerate progress in the manufacture of vaccines and therapeutics moving forward.

3. mRNA Synthesis Reagents And Manufacturing 8/14/2023

   As novel mRNA therapies are starting to enter clinical stages of development, Aldevron is providing critical support in a number of ways with specialized products and services.

4. CRISPR sgRNA For Successful Gene Editing: Discovery To Clinic 9/25/2023

   The single guide RNA (sgRNA) is one of the key components of successful CRISPR gene editing. Here we cover all the important aspects of sgRNA and Synthego’s sgRNA products.

5. Gradient Performance Of The DynaChrom Single-Use Chromatography System 3/18/2024

   Explore a single-use chromatography system that introduces micro-efficiencies into the manufacturing workflow process, potentially leading to time and cost savings throughout the production life cycle.

6. High Efficiency T-Cell Editing 11/28/2023

   Explore a modified synthetic sgRNA that allows you to achieve efficient, multigene knockout in primary human resting CD4+ T-Cells.

7. Expectations On The Pathway To GMP For Gene-Modified Cell Therapies 6/21/2023

   Learn how a robust understanding of the RNP’s critical process parameters and CQAs is crucial for ensuring product consistency, enhancing patient safety, and maintaining regulatory compliance.

8. Reduce Contamination Risks When Storing Synthetic DNA 10/30/2023

   An alternative to traditional polyethylene bags is offering cell and gene therapy manufacturers a solution to contamination concerns regarding DNA or RNA fragments.

9. Gene And Cell Therapy: Planning For Manufacturing Success Early 1/16/2023

   As gene therapy organizations are asked to balance the need for rapid clinical progression and stringent quality expectations, explore how to optimize plasmid production and reach patients with efficiency.

10. Understanding CRISPR Clinical Trials: Your Questions Answered 3/15/2023

    CRISPR technology is revolutionizing cell and gene therapies, but how do CRISPR clinical trials work? Follow this explanation of CRISPR therapies from the discovery phase to FDA approval.