RNA Supply Chain Resources

1. Key Challenges for CRISPR In Clinical Development 2/28/2023

   Learn how to approach CRISPR cell and gene therapy development challenges, such as regulatory hurdles, ensuring consistency, finding qualified and experienced staff, and obtaining GMP-Grade reagents.

2. Transitioning From Using RUO To cGMP Chemicals For Clinical Trials 10/17/2023

   Learn about the common challenges and risks associated with accelerating your molecule's timeline from lab to clinic, along with important supply chain considerations for emerging biopharma companies.

3. Review Of mRNA Vaccines & Therapeutics Manufacturing Challenges: Plasmid DNA Manufacturing 6/7/2022

   This review suggests technical remedial options for the production of pDNA and focuses on mRNA synthesis, purification, and encapsulation.

4. Expectations On The Pathway To GMP For Gene-Modified Cell Therapies 6/21/2023

   Learn how a robust understanding of the RNP’s critical process parameters and CQAs is crucial for ensuring product consistency, enhancing patient safety, and maintaining regulatory compliance.

5. Pre-Banking And Avoiding Manufacturing Challenges For GMP Plasmids Containing Unstable Sequence Regions 4/21/2021

   Ensuring consistent replication and proper retention of plasmid DNA sequence is vital to the economics and efficiency in generating starting materials used for production of AAV delivered gene therapy and mRNA vaccines and therapeutics.

6. Gene And Cell Therapy: Planning For Manufacturing Success Early 1/16/2023

   As gene therapy organizations are asked to balance the need for rapid clinical progression and stringent quality expectations, explore how to optimize plasmid production and reach patients with efficiency.

7. Enabling CDMOs To Focus On Core Priorities 4/26/2024

   Explore innovative solutions for CDMO's striving to remain competitive as the biopharmaceutical market grows and evolves.

8. Leveraging Single-Use Technology For mRNA-LNP Drug Manufacturing 6/12/2023

   Single-use technology is vital for ensuring the quality and expedited market entry of genomic medicines. Learn how LNP technology is paving the way for a new era of personalized, precise medicine.

9. mRNA Synthesis Reagents And Manufacturing 8/14/2023

   As novel mRNA therapies are starting to enter clinical stages of development, Aldevron is providing critical support in a number of ways with specialized products and services.

10. The Key To Improving Global Supply Chain Resilience 6/10/2024

    Explore the past, present, and future of supply chain security, ways the biopharma industry can secure supply chains and minimize risks, and more.