RNA Supply Chain Resources

1. Pre-Banking And Avoiding Manufacturing Challenges For GMP Plasmids Containing Unstable Sequence Regions 4/21/2021

   Ensuring consistent replication and proper retention of plasmid DNA sequence is vital to the economics and efficiency in generating starting materials used for production of AAV delivered gene therapy and mRNA vaccines and therapeutics.

2. Key Challenges for CRISPR In Clinical Development 2/28/2023

   Learn how to approach CRISPR cell and gene therapy development challenges, such as regulatory hurdles, ensuring consistency, finding qualified and experienced staff, and obtaining GMP-Grade reagents.

3. Where Can Novel Non-Viral Polymeric Delivery Agents Take Us? 1/18/2023

   Explore ongoing work to harness different types of HDR templates in order to build cutting-edge systems with the potential to enable point-of-care cell and gene therapy manufacture.

4. Reduce Contamination Risks When Storing Synthetic DNA 10/30/2023

   An alternative to traditional polyethylene bags is offering cell and gene therapy manufacturers a solution to contamination concerns regarding DNA or RNA fragments.

5. The Key To Improving Global Supply Chain Resilience 6/10/2024

   Explore the past, present, and future of supply chain security, ways the biopharma industry can secure supply chains and minimize risks, and more.

6. The Evolution Of Nucleotide Production 4/2/2025

   From harsh chemicals to gentle enzymes: Explore the groundbreaking shift in nucleotide synthesis, making drug manufacturing cleaner, greener, and more efficient.

7. Review Of mRNA Vaccines & Therapeutics Manufacturing Challenges: Plasmid DNA Manufacturing 6/7/2022

   This review suggests technical remedial options for the production of pDNA and focuses on mRNA synthesis, purification, and encapsulation.

8. Overcome Vaccine Development Complexities With The Right Supply Chain Partner 7/5/2022

   Explore the challenges impacting clinical supply chains and solutions to overcome these complexities, and understand why it is crucial to pick the right supply chain provider for vaccine storage and distribution.

9. Enabling CDMOs To Focus On Core Priorities 4/26/2024

   Explore innovative solutions for CDMO's striving to remain competitive as the biopharmaceutical market grows and evolves.

10. cGMP Assurance of Supply Services 1/23/2024

    Explore the stocking solution offered to a mid-sized CDMO in need of a high volume of safety stock inventory to support their customer portfolio growth.