RNA Manufacturing Resources

  1. How LNP Technology Meets The Delivery Need Of saRNA Vaccines 6/22/2023

    Explore challenges to the successful development of RNA-based drugs and vaccines as well as the advantages of utilizing lipid nanoparticle technology as a delivery platform for saRNA.

  2. Essential Strategies For IVT Optimization 11/21/2024

    Optimizing in vitro transcription (IVT) for mRNA is crucial to improving the stability of these molecules and enabling their large-scale production.

  3. Downstream Process For Gene Therapy, Plasmid-DNA Vaccine Development 6/10/2021

    A guide to plasmid DNA downstream process development including clarification, TFF, chromatography, and sterile filtration unit operations.

  4. Data Processing For Mass Confirmation, Impurities Analysis Of Oligos 5/5/2022

    Explore an automated, compliance-ready LC-MS workflow for intact mass confirmation and purity analysis of synthetic oligonucleotides including siRNA and large single guide RNA oligonucleotides.

  5. Understanding CRISPR Clinical Trials: Your Questions Answered 3/15/2023

    CRISPR technology is revolutionizing cell and gene therapies, but how do CRISPR clinical trials work? Follow this explanation of CRISPR therapies from the discovery phase to FDA approval.

  6. Exosome Isolation By TFF And Size Exclusion Chromatography 3/6/2024

    Here, we demonstrate a scalable workflow for the isolation of exosomes that combines tangential flow filtration for the concentration of exosomes followed by gentle size exclusion chromatography.

  7. Demand More From Your Oligo Synthesizer 3/4/2024

    The market for oligonucleotide therapeutics is expanding, and the pipeline is diverse. Gain insight into how you can fast-track your molecule's development with verified synthesizers, columns, and scientific support and expertise.

  8. Building Local Biomanufacturing Capacity In South Africa 2/11/2025

    Biovac evolved from a vaccine supplier to a biopharmaceutical innovator, providing a blueprint for expanding Africa's vaccine manufacturing capacity. Gain valuable insights from their journey.

  9. Leveraging Single-Use Technology For mRNA-LNP Drug Manufacturing 6/12/2023

    Single-use technology is vital for ensuring the quality and expedited market entry of genomic medicines. Learn how LNP technology is paving the way for a new era of personalized, precise medicine.

  10. Tackling Antimicrobial Resistance 5/14/2024

    Learn how three companies collaborated to develop a new antibiotic to address the increasing development of antimicrobial resistance (AMR) that threatens the global health landscape.