RNA Manufacturing Resources

  1. Compatible Platforms For Microbial Identification 11/21/2023

    Reduce the time-to-results for microbial identification by taking advantage of the shorter run cycle and off-instrument data analysis provided by this optimized and validated workflow.

  2. Genome Editing of Human Primary T Cells With Lipid Nanoparticles 4/18/2022

    We show CRISPR/Cas9-mediated knockouts of the T cell receptor and explore multi-step LNP engineering to produce TCRÉ‘β KO CAR T cells, a promising approach towards allogeneic CAR T cell therapy.

  3. Size Matters: Mastering Size Exclusion For Oligos 12/15/2025

    Learn how to separate molecules strictly by size, effectively remove salts, and select the correct pore specifications for a gentle, non-destructive purification workflow.

  4. RNA Polymerases For Efficient mRNA Manufacturing 2/9/2026

    Precise enzyme selection in IVT reduces dsRNA byproducts and boosts capping efficiency. This ensures high-quality mRNA production while easing the burden of complex downstream purification processes.

  5. Downstream Process Development For Efficient Purification Of Adenovirus 9/10/2018

    Here, we describe the development of two effective downstream processes for purification of adenovirus from cell culture harvest.

  6. mRNA-LNP Nucleic Acid Assessment From Distinct Formulations 9/8/2023

    Review a showcase of a high throughput robust analysis for nucleic acid integrity and size assessment of mRNA-LNP samples using a multi-capillary system and purity and integrity analysis kit.

  7. CMC And Regulatory Considerations For CRISPR Therapies 3/21/2024

    This article explores the details of Chemistry, Manufacturing, and Controls and Critical Quality Attributes, which play an important role in gene editing.

  8. Achieving Operational Efficiency In Today's Fragmented Market 7/26/2019

    Meeting the goals of today’s industry requires a deeper look at how to continuously achieve maximum utilization and reduce waste without sacrificing quality in the race to be first to market. 

  9. mRNA Manufacturing And Formulation 11/15/2022

    From fermentation to formulation, mRNA manufacturing requires a toolbox of technologies, services, and expertise. Explore our portfolio of solutions for making, purifying, and formulating mRNA.

  10. Fast Track RNA-LNP Drug Development By Lowering The Lipid Barrier 8/21/2023

    Fast-track RNA-LNP development, streamline screening with off-the-shelf ionizable lipid mixes, and utilize validation strategies to generate reproducible and scalable LNPs for lead candidates.