RNA Manufacturing Resources

  1. Modeling The Economics Of Vaccine Manufacturing 5/26/2023

    Here, we describe the use of a custom-designed cost model to explore the economics of vaccine manufacturing when using different modalities.

  2. Tips For Viral Vector Production 4/16/2024

    Learn about how meticulous purification optimization can maximize recovery and impurity removal by leveraging scalable downstream technologies to meet regulatory and process economy requirements.

  3. Meeting Regulatory Requirements With Confidence 6/7/2024

    An outbreak of mycoplasma can halt a biopharmaceutical facility's production for months. Explore the impact of mycoplasma contamination and the most accurate and sensitive way to detect it.

  4. The Execution Stage Of Technology Transfer 5/2/2024

    What are the key elements in the readiness stage of a technology transfer that are critical to your success? Explore Process Performance Qualification (PPQ) and the execution stage of PDA TR-65.

  5. Lipid Nanoparticle Development, Manufacturing Advance Novel Therapeutics 3/22/2022

    An effective partner must possess the necessary unique analytical capabilities for LNP characterization and the ability to support clients from concept to commercialization.

  6. The Benefits Of Cas9 mRNA: Precision, Control, Cost Efficiency 4/26/2024

    Unlock the full potential of CRISPR-Cas9 gene editing with high-purity Cas9 mRNA, the emerging choice for safer and more efficient genome engineering.

  7. Exosome Isolation By TFF And Size Exclusion Chromatography 3/6/2024

    Here, we demonstrate a scalable workflow for the isolation of exosomes that combines tangential flow filtration for the concentration of exosomes followed by gentle size exclusion chromatography.

  8. Understanding The Microfluidic Platforms For Scaling Nanoparticle Production 10/13/2022

    Learn about the benefits of microfluidics for nanoparticle production over traditional methods as well as scaling nanoparticle production for clinical or industrial use.

  9. Residual Plasmid Quantification In Gene Therapy Manufacturing Workflows 6/7/2024

    This article details the design and application of a Plasmid DNA - Kanamycin Resistance Gene (pDNA-KanR) kit for residual plasmid quantification in gene therapy manufacturing.

  10. New To mRNA Manufacturing? Considerations For Starting 6/15/2022

    Explore considerations for starting mRNA manufacturing related to the following topics: DNA template, mRNA product - IVT, mRNA product - purification, LNP encapsulation, and fill-finish.