RNA Manufacturing Resources

  1. New Hope For Neuronal Diseases With Polymer Nanoparticle-Based Gene Therapy 1/28/2025

    A new polymer nanoparticle (PNP) system enables targeted delivery of large genetic payloads to neuronal cells, advancing gene therapies for NF1 and other nervous system disorders.

  2. Production And Clarification Of Lentiviral Vectors 10/30/2024

    Explore scalable processes for lentiviral vector production and clarification at the 50 L scale, utilizing the CTS LV-MAX system and single-use bioreactors for robust gene therapy manufacturing.

  3. A Novel RNA Lipid Nanoparticle Platform: Gene-Edited CAR T Cells For Off-The-Shelf Cancer Therapy 4/14/2022

    We report on the use of a novel lipid nanoparticle (LNP) reagent in a validated protocol to achieve successful complex gene editing in primary T cells with high efficiency while maintaining high cell viability.

  4. CDMO Uses Robotic Gloveless Isolator For Advanced Therapeutics 4/28/2025

    CDMOs must innovate production architectures to meet the demands of advanced therapeutics to ensure a reliable supply and compliance. Discover how these approaches advance modern medicine and improve patient outcomes.

  5. A Guide To mRNA Vaccine Production And Manufacturing Services 7/13/2023

    Find out more about the key steps for successful mRNA vaccine production, which encompasses mRNA manufacturing, and ways that you can save valuable time from the start of manufacturing.

  6. Discussing mRNA: Challenges And Opportunities For Scale-Out And Optimization 2/6/2024

    In a recent Cell & Gene Live event, experts explored challenges surrounding raw materials – both quality and supply – as well as the importance of achieving more efficient scale-out and turnaround times for mRNA production.

  7. The Value Of Premium Gibco Peptones 5/10/2024

    Achieve the optimal nutritional balance with diverse supplements tailored for your specific bioprocess that can be added to maintain a nutritionally balanced medium.

  8. Standardize Scale-Up And Reduce Time To Market With Mixing Cartridges 7/21/2023

    Despite the momentum of the RNA-LNP therapeutic market, significant manufacturing challenges remain. However, the right mixing could solve three of these key challenges regarding instrumentation.

  9. mRNA Process And Cost Modeling: A Tool To Optimize Process Development

    Demand for mRNA-based medicine production continues to increase, as do investments in prophylactic and therapeutic indications. Explore a cost-model that compares all modalities.

  10. Accelerating The Development And Scale-Up Of mRNA Vaccines 3/2/2022

    Learn how downstream considerations can make the difference between success and failure on the path towards the commercialization of mRNA vaccines.