RNA Analytical Quality/Resources

  1. CRISPR Off-Target Editing: Prediction, Analysis, And More 2/28/2025

    A crucial consideration for researchers is off-target editing – unintended DNA modifications at sites other than the intended target. Explore the complexities and strategies to mitigate these effects.

  2. The Sleek Science Of Ion Pair (IP)-Reversed Phase (RP) Oligonucleotide Analysis 12/15/2025

    Master oligonucleotide separation by balancing hydrophobic and ionic interactions. Learn how selecting the right cationic pairing agent optimizes retention and ensures compatibility with mass spectrometry workflows.

  3. Lentiviral Vector Characterization For Cell And Gene Therapy Manufacturing 6/20/2024

    This study focuses on characterizing recombinant LVVs used in gene-modified cell therapies, utilizing two real-time PCR assays adapted to the QuantStudio™ Absolute Q™ Digital PCR System.

  4. Advancing RNA-LNP Therapeutics As An Alternative To Viral Vectors 11/17/2025

    RNA-LNP therapeutics offer a flexible, transient alternative to traditional viral vectors for genetic medicine. Learn about the advantages of LNPs in safety, scalability, and payload versatility.

  5. Why Bioanalysis Needs To Break Free From Manual Bottlenecks 9/2/2025

    Bioanalysis remains one of the most persistent bottlenecks in drug development, with CROs displaying inefficiencies that are no longer operational nuisances but strategic liabilities.

  6. Assigning IR Absorption Bands For RNA Building Blocks Using Microfluidic Modulation Spectroscopy 1/13/2025

    Explore the power of MMS in identifying RNA base signatures. This study analyzes vibrational modes of A, G, C, and U, revealing insights into electronic environments and molecular interactions.

  7. Enabling Effective Passive And Active Immune Cell Targeting Strategies 8/10/2026

    Targeted LNPs that bypass the liver and home to the spleen could reshape in vivo CAR T cell manufacturing. See the data behind the approach.

  8. Suitability Testing For IVT mRNA Analysis 11/20/2025

    Automated capillary electrophoresis provides robust, precise analysis of IVT mRNA integrity, concentration, and size, demonstrating excellent method precision.

  9. The Evolution Of Nucleotide Production 4/2/2025

    From harsh chemicals to gentle enzymes: Explore the groundbreaking shift in nucleotide synthesis, making drug manufacturing cleaner, greener, and more efficient.

  10. How Automated NGS Solutions Advance Rare Disease Research 2/27/2026

    See how a unified NGS workflow is helping a major pediatric genetics lab boost efficiency, manage growing sample volumes, and accelerate insights into rare diseases through streamlined automation.