The Evolution Of Nucleotide Production: A Roche CustomBiotech Journey

For decades, traditional chemical synthesis dominated nucleotide production, but it came with significant drawbacks—organic solvent use, contamination risks, and environmental concerns. With the growing demand for safe and sustainable biopharmaceutical manufacturing, the industry needed a paradigm shift. Enter enzymatic synthesis: a nature-inspired approach that eliminates harmful chemicals while delivering high-purity nucleotides. This transformation has not only improved manufacturing efficiency but also aligned with global sustainability goals.

In this article, we trace the evolution of nucleotide production, examining the challenges of the past and the innovations shaping the future. Join us as we explore how enzymatic synthesis is setting new industry standards.